background: after improvements in various cancer treatments, life expectancy has been raised, but success in treatment causes loss of fertility in many of the survived young men. cryopreservation of immature testicular tissues or cells introduced as the only way to preserve fertility. however, freezing has some harmful effects. melatonin, a pineal gland hormone, has receptors in reproductive sy...

A large body of evidence supports the protective role flavonol antioxidant compound quercetin in mammals. We tested hypothesis that can protect against hypothalamus-pituitary-gonadal (HPG) axis defect like a reduction gonadotropins and testicular hormones abnormal semen analysis induced by chronic unpredictable stress (CUS), possibly via downregulation oxidative (ROS) p53-Bax-caspase-3 pathways...

Introduction: Testicular microlithiasis is an uncommon condition characterized by calcifi cations within the seminiferous tubules. The true prevalence in a normal population has not been defi ned. Methods: A review of the literature with emphasis on the connection between testicular microlithiasis and testicular malignancy was carried out. Results: Testicular microlithiasis is associated with d...

introduction: anabolic – androgenic steroids (aas) are used at high doses by athletes for improving athletic ability, muscle mass and physical appearance. unfortunately, the abuse of these agents has been significantly increased. it has been established that exercise and high doses of aas may influence the hypothalamic-pituitary-gonadal axis, which can in turn affect testicular apoptosis and ma...

AIM To evaluate the relationship between testicular function and testicular volume measured by using Prader orchidometry and ultrasonography (US) to determine the critical testicular volume indicating normal testicular function by each method. METHODS Total testicular volume (right plus left testicular volume) was measured in 794 testes in 397 men with infertility (mean age, 35.6 years) using...

OBJECTIVE To prospectively determine the prevalence of testicular microlithiasis in symptomatic patients who were referred for scrotal ultrasound examination and to evaluate the possible association of testicular microlithiasis with testicular cancer and other conditions such as cryptorchidism or history of ascending testis. MATERIALS AND METHODS 391 men who were referred to our institutions ...

background: spermatogonial stem cells are subpopulation of spermatogonial cells in testis tissue that support beginning and maintenance of spermatogenesis. ubiquitin carboxy-terminal hydrolase l1 (uchl1) could be a specific marker for identification of spermatogonial stem cells including spermatogonial sperm cells (sscs) in testis tissue and during the culture; therefore we undertook this study...

BACKGROUND Testicular biopsy is an acknowledged method of examination of the testes for diagnostic and therapeutic purposes. We describe the pattern of testicular histologies in our environment. MATERIALS AND METHODS We carried out a retrospective review of testicular histology results from the Pathology Department of Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, over a 5-year p...

PURPOSE We assessed reproductive and testicular function in adult rats after testicular torsion created before, during and after puberty, and with vs without resveratrol or arginine treatment. MATERIALS AND METHODS Age matched rats were divided into groups, including simulated surgery without testicular torsion, 720-degree testicular torsion for 4 hours, testicular torsion with resveratrol tr...

Purpose: To determine prospectively the prevalence of testicular microlithiasis in symptomatic patients who were referred for scrotal ultrasound examination and to evaluate the possible association of testicular microlithiasis with testicular cancer. Material and method: 391 men who were referred to our institution between July 02 and May 05 for any type of symptoms from the testicles underwent...