Hemophagocytic syndrome (HPS) is an uncommon manifestation in systemic lupus erythematosus (SLE). Clinical features of HPS include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. HPS comprises primary and reactive forms. Herein, we describe a case of untreated SLE with HPS as one of the first manifestations of systemic Lupus.

Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis that is included in the pulmonary-renal syndromes. Although glomerulonephritis represents the major clinical feature of MPA indicative of renal involvement, diffuse alveolar haemorrhage is the classic manifestation of pulmonary involvement. However, pulmonary fibrosis is a less frequently reported pulmonary manifestation. Here...

Symptoms of primary systemic amyloidosis include neuropathy, myopathy, and cardiac or renal insufficiency; multiple organ systems are often involved. Amyloidosis can involve both the central nervous system and peripheral nerves. Amyloid myopathy is a rare manifestation of primary systemic amyloidosis. It is less well recognized that amyloid can directly infiltrate and weaken skeletal muscle. Li...

Gastric antral vascular ectasia is a not so well-understood, and more rare, gastrointestinal manifestation of Systemic Sclerosis which can lead to chronic anemia. A high suspicion and better understanding of this rare manifestation is needed for early detection and treatment. Therapeutic regiments include iron supplementation with acid suppressive therapy, while endoscopic intervention has been...

Osteoporotic fractures in elderly women are mainly due to postmenopausal bone loss but can sometimes be caused by a disabling haematological disease. We describe an 84-year-old woman suffering from multiple osteoporotic fractures as a manifestation of mast cell leukaemia. Mast cell leukaemia is a rare form of systemic mastocytosis with a poor prognosis and very few therapeutic options. Osteopor...

The temporal interval between flashing lights that is required to perceive nonsimultaneity decreases as the refractive error increases from 0 to +2 diopters. The interval then remains constant with further increases to 3 and 4 diopters. The results are discussed in terms of the relative increase of transient to sustained visual channels and of the increase in apparent movement.

1 of 2 DESCRIPTION The manifestations of Langerhans cell histiocytosis (LCH) are legion in both local and systemic variants. About 15–61% patients with LCH have otologic involvement; this manifestation is more frequent in children with multisystem disease and a primary manifestation in 5–25% of patients. Among otologic lesions, solitary external ear LCH, as the only site of clinically non-progr...

IMPORTANCE Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma and may rarely infiltrate the ocular structures. Ophthalmic findings in MF can be highly variable. The most commonly involved ocular tissue is the eyelid skin, but intraocular involvement can be seen in patients with extensive systemic disease. To our knowledge, an isolated eyelid mass as an initial manife...

Visual disturbances during transurethral resection (TUR) of the prostate are described and possible causes of this phenomenon are discussed. Awareness of this unusual manifestation of the TUR reaction may offer the first clue to excessive systemic absorption of irrigation fluid.