BACKGROUND Several plant extracts from Rutaceae family are currently used to the management of sickle cell disorder (SCD) in the African. Few reports have shown that extracts from Zanthoxyllum or Fagara genus demonstrated anti-sickling property. This study investigates the in vitro antisickling and antioxidant properties of extracts from Zanthoxyllum heitzii. METHODS The sickling of red blood...

The leaching process of cobalt using a wide range experimental variables is described. treated samples were from the Kalumbwe Mine in south Democratic Republic Congo. In this study, predictive model recovery both Taguchi statistical method and an artificial neural network (ANN) algorithm was proposed. utilising L25 (55) orthogonal array ANN multi-layer, feed-forward, back-propagation learning a...

BACKGROUND Inhaled frusemide but not bumetanide, another loop diuretic, reduces bronchial responsiveness to sodium metabisulphite (MBS). To investigate whether the effect of frusemide could be mediated through mechanisms other than Na+/K+/Cl- cotransporter inhibition, the effects of amiloride--an inhibitor of sodium channels in the airway epithelium--and of acetazolamide--a specific inhibitor o...

The extraction of Canna edulis Ker. starch from its rhizome was performed using 2 different types of press (hydraulic press and screw press) and with the addition of Na-metabisulphite and NaOH (in the range of concentration 100 5000 ppm each). The optimum condition for this process was determined by Central Composite Design of experiment and the statistical calculation was solved by Design-Expe...