Taking medical history, physical examination, and performing some in vivo and in vitro tests are necessary for the diagnosis of allergy. Skin prick test (SPT) is considered as the standard method and first-line approach for the detection of allergic sensitization. Although mainly SPT is used for the detection of allergic sensitization, intradermal skin test (IDST) may be necessary, especially i...

We measured the microvascular response to histamine in guinea pig skin. Histamine (40 mg ml(-1)) was given either as a skin prick test or applied topically onto a skin window. The skin window was prepared by applying suction and gentle warming to the skin so that a blister was formed, and by removing the top of the blister. The microvascular response was measured as the accumulation of radiolab...

delayed-type hypersensitivity (dth) reaction measured by skin testing is an important indicator for evaluation of cellular immune response in leishmaniasis. skin testing in leishmaniasis, known as leishmanin or montenegro test, is used normally for immunoepidemiological studies and for diagnosis. in cutaneous leishmaniasis (cl), the skin test is positive during the active phase of disease and r...

BACKGROUND The dissociation between specific IgE and skin prick test reactivity to aeroallergens, a common finding in populations living in low and middle-income countries, has important implications for the diagnosis and treatment of allergic diseases. Few studies have investigated the determinants of this dissociation. In the present study, we explored potential factors explaining this dissoc...

BACKGROUND Dental practitioners, like other health care providers who regularly use latex gloves, are at increased risk for latex sensitivity. They are also at risk for irritant or allergic contact dermatitis. OBJECTIVE This study was carried out to determine the prevalence of latex sensitivity and possible risk factors in staff and students of a Faculty of Dentistry. METHODS A cross-sectio...

Background Diagnosis of food allergy relies on clinical history, tests for allergen specific IgE and oral food challenges. A recent reaction consistent with IgE-mediated symptoms in conjunction with a positive allergen-specific IgE test (either skin prick test (SPT) or serum allergen specific IgE (sIgE)) is usually sufficient to diagnose food allergy. In the absence of a reaction history, a pos...

PURPOSE We previously reported that the skin prick test was sensitive and the serum specific immunoglobulin E test was specific for predicting positive airway responses to house dust mites (HDMs) in patients with asthma. Because the nose and bronchus are one airway, the nasal provocation test would be more specific for predicting the bronchial responses to HDM than the skin test. METHODS The ...

BACKGROUND Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensitization patterns may change with age. OBJECTIVE To determine the predictors of allergen sensitization in the first 3 years of life in the growing up in Singapore towards health...

Objective: To identify the responsible allergens in patients with allergic rhinitis using skin prick test and further to help create the chart showing allergen distribution in Duzce region of Turkey. Methods: This retrospective case series included 192 patients diagnosed with allergic rhinitis between June 2014 and June 2016 in the private office of the author. The diagnosis of allergic rhiniti...

Hypersensitivity reactions to oxaliplatin have been increasing since its introduction at the end of the 1990s, but allergy tests with antineoplastic drugs are rarely used to aid diagnosis. We describe 5 cases in which hypersensitivity reactions to oxaliplatin after several courses of chemotherapy were managed by allergy testing and desensitization. Skin prick tests were negative at 1 mg/mL in a...