BACKGROUND There is no local data about rickets available in Hazara Division, while clinical experience suggests that problem exists in this area with abundant sunlight. We carried out this study with an objective to determine presence, presentation and predisposing factors of rickets in pediatrics population of Hazara Division. METHODS This study was conducted in Department of Pediatrics, Ay...

Rickets and osteomalacia are associated with hypophosphatemia in several disease states, including X-linked hypophosphatemic rickets, autosomal-dominant hypophosphatemic rickets, and tumor-induced osteomalacia. Recent advances in the understanding of these diseases include discovery of mutations in the genes encoding human phosphate-regulating gene with homologies to endopeptidases on the X chr...

Rickets is a potentially treatable disease of the bone that is most commonly due to deficiency of vitamin D and is increasing in incidence in developed countries. Risk factors include dietary factors, the practice of covering up and darker skin pigmentation. This small retrospective case study set out to examine all cases of rickets presenting to the Paediatric Orthopaedic clinic over a 15-mont...

Moncrieff, M. W., Lunt, H. R. W., and Arthur, L. J. H. (1973). Archives of Disease in Childhood, 48, 221. Nutritional rickets at puberty. Four adolescent Asians with vitamin D deficiency rickets were seen in Derby in the 5 years 1967 to 1971. They had an extremely low intake of vitamin D, and this, combined with the extra metabolic demands of puberty, was judged to be the main cause of the rick...

Rickets is not a new disease to Egypt. Its existence dates back to ancient times. Drawings in old Egyptian tombs show that rickets existed in the times of the Pharaohs (Ruffer, 1921). Until recently (Dicks, 1922) the disease was considered to be rare in Egypt. Shawki (1928), however, demonstrated that rickets is prevalent in this country. Nearly 50 per cent. of all Egyptian infants between the ...

As long ago as 1908 it was reported' that in intestinal infantilism there was serious derangement of the mineral metabolism. A number of investigations of the calcium anid phosphorus metabolism of patients with fatty diarrhoea, both adults and children, have been made at intervals since that time. It has been consistently found that the serum calcium tended to be low, and the serum inorganic ph...

Worldwide, rickets is the most common form of metabolic bone disease in children. Despite the concept that it is a rare disease, it is on the increase in many regions, including Western Europe and the USA, and in many ethnic subgroups that have immigrated to temperate regions. Vitamin D deficiency is the main cause of rickets, though nutritional deficiency of calcium and phosphorous generates t...