Comment: I would like to suggest the coverage for Macugen be extended to the treatment of diabetic macular edema. Macugen is a selective anti-VEGF drug which has been approved for the use in exudative ARMD. The injection of Macugen in the treatment of diabetic macular edema has been shown to be effective in improving the vision of patients with diabetic macular edema in the recently published a...

UNLABELLED Diabetic macular edema (DME), one the most prevalent causes of visual loss in industrialized countries, may be diagnosed at any stage of diabetic retinopathy. The diagnosis, treatment, and follow up of DME have become straightforward with recent developments in fundus imaging, such as optical coherence tomography. Laser photocoagulation, intravitreal injections, and pars plana vitrec...

Diabetic macular edema (DME) remains the most common cause of vision loss among diabetic patients. New understanding of the underlying pathophysiology has interest in the potential benefits of the specific pharmacologic therapy, such as treatment with intraocular steroids, anti-vascular endothelial growth factor (VEGF), and protein kinase C-beta (PKCβ) inhibition. At the last time, laser photoc...

PURPOSE To evaluate the effect of pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for management of refractory diffuse diabetic macular edema (DME). METHODS In this prospective interventional case series, eyes with refractory diffuse DME unresponsive to macular photocoagulation and/or intravitreal bevacizumab, and best corrected visual acuity (BCVA) ≥ 20/200 and ≤ 20...

BACKGROUND The major cause of visual impairment in diabetic patients is macular edema. The failure of laser photocoagulation in a large subgroup of patients with clinically significant diabetic macular edema has prompted interest in other treatment methods. OBJECTIVES To evaluate the long-term efficacy and safety of an intravitreal injection of triamcinolone acetonide for clinically significa...

BACKGROUND The purpose of this retrospective chart review was to evaluate factors associated with improvement of visual acuity after a single sub-Tenon injection of triamcinolone acetonide in patients with diabetic macular edema. METHODS We reviewed the medical records for 63 consecutive eyes with diabetic macular edema treated by sub-Tenon injection of triamcinolone acetonide and assessed at...

Background: 26 million people were estimated to be affected by diabetes in 2010 across the globe. Diabetic macular edema (DME) is the most important cause of visual impairment due to diabetic retinopathy. Optical Coherence Tomography (OCT) is a non-invasive modality which produces cross-sectional or three-dimensional, high-resolution images of the retinal layers and quantitative assessment of r...

OBJECTIVE To explore the multifocal electroretinogram in patients with nonproliferative diabetic retinopathy with clinically-significant macular edema. METHODS Forty-one eyes with clinically significant macular edema were tested. The latencies and amplitudes of average responses of 5 eccentric rings from 0 to 26 degrees relative to the fixation point were compared with normal values obtained ...