Redox state is a term used widely in the research field of free radicals and oxidative stress. Unfortunately, it is used as a general term referring to relative changes that are not well defined or quantitated. In this review we provide a definition for the redox environment of biological fluids, cell organelles, cells, or tissue. We illustrate how the reduction potential of various redox coupl...

Background: Pemphigus diseases including pemphigus vulgaris (PV) and bullous pemphigoid (BP) are autoimmune diseases that cause severe blistering of the skin and mucous membranes. Among inflammatory mediators, reactive oxygen species (ROS) are involved in the pathogenesis of a wide variety of diseases through oxidative stress for which protein carbonyl (PC) and total antioxidant capacity (TAC) ...

During the past few decades, it has been widely recognized that Reduction-Oxidation (redox) responses occurring at the intra- and extra-cellular levels are one of most important biological phenomena and dysregulated redox responses are involved in the initiation and progression of multiple diseases. Thioredoxin1 (Trx1) and Thioredoxin2 (Trx2), mainly located in the cytoplasm and mitochondria, r...

This study examined the clinical and biological importance of thioredoxin-1, a redox-active defensive protein that controls multiple biological functions, in pregnant women. We measured serum concentrations of thioredoxin-1, total hydroperoxides, and redox potential in 60 pregnant women at the early third trimester: gestational age of 27-29 weeks. The thioredoxin-1 concentration (mean ± SD) was...

quinones are a class of compounds which have widespread importance in chemistry, biology and medicine. because of their appropriate performance in electron transferring rate, quinones are among the most applicable mediators in biosensors. recently, the effects of different non-metal substitutions on redox potential of quinone have been investigated to design suitable mediators for different ele...

The aim of the present study was to examine the changes occuring in the redox status in male basketball players at the beginning and end of a highly competitive season. For this purpose, the redox status of 14 professional athletes of a European basketball club was examined at 2 different time points, at the beginning (phase 1) and at the end of the season (phase 2). The redox status was assess...