نتایج جستجو برای: radioimmunotherapy

تعداد نتایج: 1230  

Journal: :Journal of Medical Imaging and Radiation Sciences 2019

Journal: :Cancer Biotherapy and Radiopharmaceuticals 2013

Journal: :Blood 2003
Bruce D Cheson

Enthusiasm for the use of monoclonal antibodies, such as rituximab, has markedly changed the approach to patients with non-Hodgkin lymphomas (NHLs). Nevertheless, more effective therapies are needed. Radioimmunotherapy as a form of targeted radiation therapy may add significantly to our therapeutic options. Yttrium Y 90 ibritumomab tiuxetan, recently approved by the Food and Drug Administration...

Journal: :Seminars in oncology nursing 2003
Arati V Rao Gamal Akabani David A Rizzieri

Non-Hodgkin's lymphoma (NHL) is the most common hematological malignancy in the United States with a rapidly increasing incidence. Most follicular NHL is indolent but incurable, whereas the more aggressive varieties do respond to therapy. Most patients with follicular NHL who transform to an aggressive NHL are very difficult to treat successfully. Treatment options have included chemotherapy, r...

2012
David M. Goldenberg Chien-Hsing Chang Edmund A. Rossi William J McBride Robert M. Sharkey

Pretargeting is a multi-step process that first has an unlabeled bispecific antibody (bsMAb) localize within a tumor by virtue of its anti-tumor binding site(s) before administering a small, fast-clearing radiolabeled compound that then attaches to the other portion of the bsMAb. The compound's rapid clearance significantly reduces radiation exposure outside of the tumor and its small size perm...

2014
Jean-Baptiste Gorin Yannick Guilloux Alfred Morgenstern Michel Chérel François Davodeau Joëlle Gaschet

Radioimmunotherapy aims to deliver radiation directly to cancer cells by means of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. We have demonstrated that α radiation can also induce immunogenic cell death, reinforcing interest in their clinical development.

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