OBJECTIVE The clinical effects of high dosage pulse glucocorticosteroid (GS) infusion as a treatment for rheumatoid arthritis (RA) differ considerably between patients. The aim of the present study was to gain more insight into these differences in clinical response. METHODS Twenty-three RA patients (6 M/17 F) with treatment-resistant active erosive disease were treated with GS pulse therapy,...

The clinical report of a 31-year-old man who developed acute renal failure due to idiopathic rapidly progressive glomerulonephritis is presented. Intravenous pulse methylprednisolone therapy in combination with cyclophosphamide resulted in marked improvement in renal function. The literature dealing with pulse therapy is reviewed.

objective: in electrochemotherapy (ect), there is an unpleasant sensation of muscle contraction when using a low frequency (1 hz). therefore, by increasing the pulse frequency above the tetanic frequency this painful sensation can be reduced. the aim of the present study is to compare the treatment efficiencies of low and high frequency ect, and estimate the effect of its repeated sessions. mat...