1. In these studies several phases of the predpitm reactions were investigated by the use of purified proteins as antigens. These preparations were edestin from hemp-seed and crystalline ovalbumin from fresh eggs. The ovalbumin, isolated by the method of Hopkins and Pinkus,.was apparently as pure as is obtainable by chemical means. This albumin, however, produced moderately severe anaphylactic ...

OBJECTIVE To document the manifestations of syphilis among patients with concurrent HIV infection over a 12-month period. METHOD Descriptive, cross-sectional, hospital-based study of all adult patients with syphilis and HIV infection who attended the skin clinic of the University of Nigeria, Teaching Hospital, Enugu, between July 2000 and June 2001. A standardized questionnaire was used to re...

A paraprotein can be defined in our present state of knowledge as a complete or incomplete immunoglobulin molecule, possibly abnormal, produced in excess by a single clone of immunocytes (Osserman and Fahey, 1968), and characterized on electrophoresis by a discrete band or peak. The discovery of a paraprotein in the plasma should not be regarded as synonymous with a malignant proliferative dise...

BACKGROUND  The World Health Organization recommends that malaria treatment be based on demonstration of the infecting Plasmodium parasite specie. Malaria rapid diagnostic tests (RDTs) are recommended at community points of care because they are accurate and rapid. We report on parasitological results in a malaria study in selected rural communities in 3 African countries. METHODS  In Nigeria...

Blood Grouping. It is essential that the stock agglutinating sera used are of satisfactory potency and devoid of prozone phenomenon (inhibitory action, when undiluted). Such sera should have an initial agglutinin titre of at least I in Ioo and will then remain reliable, even at room temperature, for at least six months (sera conforming to these standards are now available commercially from Mess...

The cytosolic glutathione S-transferase (GST) enzymes serve as ideal biomarkers of organ damage as they exhibit many of the required characteristics, i.e. specific localisation, high cytosolic concentration and relatively short half-life. The role of GSTs as early indicators of organ damage is applicable to both human and animal models. Because of the regio-specific localisation of the differen...

Aim: The aim of this study was to investigate the effect of ozone used as cavity disinfectant on dentin bond strength of resin-based restorative material. Material and Method: The study included 36 adult 3rd molar teeth removed for surgical reasons. Each tooth was set in a cylindrical mould 2cm in diameter and 3cm high with the dentin surface parallel to the occlusal level and the roots remaini...

The crossmatch has been used as the final phase of pretransfusion testing for over half a century.’ However, during this time, there have been frequent modifications of the procedure, as well as differences of opinion as to the extent of its performance. In recent years, modifications have focused on its abbreviation. When the American Association of Blood Banks first published its standards in...

In the September issue of this journal, performance of BinaxNOW for the diagnosis of malaria in a major U.S. academic medical center was reported (1). Herein, we report performance of this test in a second large academic medical center in the United States. BinaxNOW was introduced at our institution as a component of routine blood parasite examination along with thickand thin-blood-smear micros...

To the Editor: We read with interest the recent paper on the combination of serum protein electrophoresis (SPEP) and serum free light chain (FLC) assay as a potential alternative to SPEP and urine protein electrophoresis (UPEP) screening for paraproteinemia (1 ), as well as the accompanying editorial on sensitivity and specificity issues of the serum FLC assay (2 ). This assay, which first beca...