Twenty three sporadic cases of Reye's syndrome diagnosed according to widely accepted criteria were seen between 1979 and 1982. The patients were younger than those reported from North America (median age 9 months), girls were twice as common as boys, and the syndrome presented twice as frequently in the summer 6 months. The annual incidence was 1.4 cases/100 000 among children aged less than 4...

Clinicians and researchers in Canada and the United States have established a number of early intervention programs and research sites on the early course of psychosis and the prodromal period that commonly precedes psychotic disorders. In Canada, early detection and treatment programs for psychosis have been established in many areas of the country, and typically serve specific catchment areas...

OBJECTIVES This study sought to investigate the clinical and laboratory findings of patients affected by sudden-onset syncope without prodromes who had a normal heart and normal electrocardiogram. BACKGROUND The pathophysiology of syncope in these patients is uncertain. METHODS We compared the clinical and laboratory findings of 15 patients with sudden-onset syncope without prodromes who ha...

BACKGROUND Cognitive disturbances have been demonstrated in individuals with potentially prodromal symptoms in objective-neuropsychological as well as subjective-symptomatic studies. Yet, the relation between subjective and objective deficits and to different prodromal states is unclear. AIMS To explore interactions between subjective and objective cognitive measures in different prodromal st...