This account summarizes Dr. Subhash Basak’s work in the field of molecular similarity. In particular, it looks at the development and application of quantitative molecular similarity analysis (QMSA) techniques using physicochemical properties, topological indices, and atom pairs as descriptors for developing structureor property-based similarity spaces and the use of a k-nearest neighbors (kNN)...

At the root of applications for substructure and similarity searching, reaction retrieval, synthesis planning, drug discovery, and physicochemical property prediction is the need for a machine-readable representation of a structure. Systematic nomenclature is unsuitable, and notations and fragment codes have been superseded, except in certain specific applications. Connection tables are widely ...

Prodigiosins, a family of natural red pigments characterized by a common pyrrolylpyrromethane skeleton, are produced by various bacteria that first characterized from Serratia marcescens. This pigment is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and anti-proliferative activity. From an industrial point of view to obtain optimal conditions to ...

Plants gums are complex mixtures of different polysaccharides with a variety of biological activities and pharmaceutical applications. Few studies have focused on physicochemical and biological properties of gums obtained from different plants. This study was designed to determine potential pharmaceutical and pharmacological values of the gum exudates and its isolated biopolymers obtained from ...

Plants gums are complex mixtures of different polysaccharides with a variety of biological activities and pharmaceutical applications. Few studies have focused on physicochemical and biological properties of gums obtained from different plants. This study was designed to determine potential pharmaceutical and pharmacological values of the gum exudates and its isolated biopolymers obtained from ...