neutralization effects of acorus calamus and withania somnifera root extracts were tested against echis carinatus venom. both plant extracts were effectively neutralized the various pharmacological activities induced by echis carinatus venom. about 0.14 mg of acorus calamus and 0.16 mg of withania somnifera root extracts were able to completely neutralize the lethal activity of 2ld 50 of echis ...

the clinical and economic importance of heart failure is widely recognized.   the incidence of heart failure is on the increase, particularly with the aging of the population around the world.   it is time for a paradigm shift in heart failure management. alternative non-pharmacological strategies to remodel the failing ventricle will shape a major portion of heart failure therapy in the decade...

Obesity is associated with metabolic derangements such as insulin resistance, inflammation and hypercoagulobility which can all be understood as consequences of adipose tissue dysfunction. The potential role for adipose tissue derived cytokines and adipokines in the development of vascular disease and diabetes may produce a clinical need to influence adipose tissue function. Various pharmacolog...

Interest in the treatment of nightmares has greatly increased over the last several years as research has demonstrated the clinical significance of nightmare disorder. This paper provides an overview of nightmare disorder, its clinical relevance, and the leading treatments that are available. In particular, the paper defines nightmare disorder and then summarize the recent literature examining ...

Endometriosis is a benign disease of the female genital system, characterized by the appearance of endometrial tissue outside the uterus. Endometriosis commonly affects the women of 25-29 age group. Main symptoms are pelvic pain and infertility. Many studies have suggested that endometriosis has a profound but negative impact not only on their social life but also on their personal life. Quanti...

Primary headaches represent highly prevalent diseases in childhood and adolescence. Unlike in adulthood, in children the most common primary headache is migraine, while tension-type headache (TTH) is less diffused, especially up to 10 years of age. Cluster headache is to be considered exceptional, showing a prevalence of 0.1%. While in TTH painful attacks are often of weak intensity and do not ...

According to the guidelines of the European Stroke Organization (ESO) and the American Stroke Association (ASA), acute stroke patients should be managed at stroke units that include well organized pre- and in-hospital care. In ischemic stroke the restoration of blood flow has to occur within a limited time window that is accomplished by fibrinolytic therapy. Newer generation thrombolytic agents...