introduction: the complex geometry of breast and also lung and heart inhomogeneities near the planning target volume (ptv) result in perturbations in dose distribution. this problem can result in overdosage or underdosage in the match region of the three treatment fields. the purpose of this study is to create a homogeneous dose distribution in the match region between the supraclavicular and t...

background: premature chromosome condensation (pcc) is a method for interphase chromosome analysis in biodosimetry. this study was performed to verify the usefulness of pcc induced by calyculin a in human peripheral blood lymphocytes (pbl) for biological dosimetry and possible construction of dose-response curve. materials and methods: peripheral blood was obtained from a healthy donor and expo...

introduction in this study, we aimed to calculate dose enhancement factor (def) for gold (au) and iron (fe) nanoparticles (nps) in brachytherapy and teletherapy, using monte carlo (mc) method. materials and methods in this study, a new algorithm was introduced to calculate dose enhancement by aunps and fenps for iridium-192 (ir-192) brachytherapy and cobalt-60 (co-60) teletherapy sources, using...

introduction: brachytherapy is a type of radiotherapy in which radioactive sources are used in proximity of tumors normally for treatment of malignancies in the head, prostate and cervix. materials and methods: the cs-137 selectron source is a low-dose-rate (ldr) brachytherapy source used in a remote afterloading system for treatment of different cancers. this system uses active and inactive sp...

Introduction: Wedge filters are used in radiotherapy to modify photon beam and improve dose uniformity in the target volume. Determination of wedge dose distribution is important to improve treatment planning accuracy. The utilization of treatment planning software to obtain dose distribution is not always available. In this work an analytical model has been developed to calcu...

Background. Individual sensitivity to isoniazid in tuberculosis patients is determined by the presence of N-acetyltransferase 2 (NAT2) enzyme gene allelic variants genome. Evaluation quantitative and qualitative alterations peripheral blood can be used for diagnosis, disease severity estimation, or as a clue estimation anti-tuberculosis chemotherapy effectiveness safety. Aim: Find associations ...