the effects of hydroalcoholic extract of peganum harmala seeds (eps) on spontaneous rhythmic contractions of isolated rat uterine was investigated in this study. eps was tested on the isolated uterus and endometrium free (i.e. stripped myometrium) preparations. eps was found to exhibit significant spontaneous contractions of the uterus and stripped myometrium relative to the solvent control. af...

the seeds of peganum harmala l. ( pgh ) (zygophyllaceae) have been used in moroccan traditional medicine for treatment of a various diseases and to relieve dolorous process. the major objective of this paper was to investigate the analgesic effect of ethyl acetate (eae), butanolic (be) and aqueous (aqe) extracts of seeds of peganum harmala and elucided the possible underlying action mechanism o...

Medicinal plants and their derivations are used as safe agents for the treatment of parasitic diseases. This preliminary study investigates antileishmanial activities Peganum harmala essential oil (PHEO), Achillea millefolium oils (AMEO) combinations against Leishmania infantum promastigotes. A standard strain L. promastigote was cultured in a 96-well Novy-MacNeal-Nicolle media culture glucanti...

Acanthamoeba castellanii is member of free living amoeba that may cause painful sight-threatening keratitis and life threatening encephalitis which involves central nervous system. Treatments for both infections are problematic because of the amoebic cysts resistance to therapeutic agents. Here we evaluated in vitro strength of methanolic seed extract of Peganum harmala on Acanthamoeba cysts an...