OBJECTIVE To determine elution characteristics of bone morphogenetic protein (BMP)-2 from a polycaprolactone coating applied to orthopedic implants and determine effects of this coating on osseointegration. ANIMALS 6 sheep. PROCEDURES An in vitro study was conducted to determine BMP-2 elution from polycaprolactone-coated implants. An in vivo study was conducted to determine the effects on o...

statement of the problem delayed loading is one of the anxieties of implant patients. immediate loading can solve the problem and make patients more satisfied. purpose the present study was aimed to compare the marginal bone level in periapical radiographs of maxi implants under different loading (immediate and delayed) patterns. material and methods this split mouth experimental study included...

The innovation by P.I Branemark that bone tissue can adhere permanently to implant surface was a clinical breakthrough in oral rehabilitation. There are several reports by most of the authors which demonstrate the success of implants. The mean age of the implants is increasing in day today life. There are certain factors to be considered in maintaining the success rate of implants through proce...

The aim of the article is to present recent developments in material research with bisphenyl-polymer/carbon-fiber-reinforced composite that have produced highly influential results toward improving upon current titanium bone implant clinical osseointegration success. Titanium is now the standard intra-oral tooth root/bone implant material with biocompatible interface relationships that confer p...

Methods to improve osseointegration that include implantation of rhBMP-2 with various kinds of carriers are currently of considerable interest. The present study was conducted to evaluate if the rhBMP-2 loaded β-TCP microsphere-hyaluronic acid-based powder-like hydrogel composite (powder gel) can act as an effective rhBMP-2 carrier for implantation in host bone with a bone defect or poor bone q...

STUDY DESIGN This was a biomechanical push-out testing study using a porcine model. OBJECTIVE The purpose was to evaluate the strength of implant-bone interface of a porous titanium scaffold by comparing it to polyetheretherketone (PEEK) and allograft. SUMMARY OF BACKGROUND DATA Osseointegration is important for achieving maximal stability of spinal fusion implants and it is desirable to ac...

Dental implants with proper antibacterial ability as well as ideal osseointegration are being actively pursued. The antimicrobial ability of titanium implants can be significantly enhanced via modification with silver nanoparticles (Ag NPs). However, the high mobility of Ag NPs results in their potential cytotoxicity. The silver plasma immersion ion-implantation (Ag-PIII) technique may remedy t...

Osseointegration can be defined as a direct structural and functional link between bone implant surface. Asymptomatic rigid fixation of the alloplastic material in is crucial for stability long-term success dental treatment. The connection surrounding tissue extremely dynamic. This interaction basis formation new structure—the implant-tissue interface. process osseointegration combination biolo...

BACKGROUND An implant coating with poly(D, L-lactide) (PDLLA) releasing incorporated zoledronic acid (ZOL) has already proven to positively effect osteoblasts, to inhibit osteoclasts and to accelerate fracture healing. Aim of this study was to investigate the release kinetics of the chosen coating and the effect of different concentrations of ZOL locally released from this coating on the osseoi...

I the 35 years since the concept of osseointegration was first applied to human patients, there have been many advances in the understanding and application of implant dentistry as a method for the replacement of missing teeth. Osseointegration as first defined by Brånemark is a scientific milestone that delineates a certain sense of separation of the old from the new in implant dentistry. Osse...