Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using current drug in ALL patients has decreased effectiveness such therapy. Therefore, a study needs be conducted identify potential new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells vitro vi...

Transition-metal-free LiCl-promoted cross-coupling reactions of tetraphenyltin, trichlorophenyl-, dichlorodiphenyl-, and chlorotriphenylstannanes with aryl halides in DMF provided access to biaryls in good to high yields. Up to four phenyl groups were transferred from the organostannanes substrates. The aryls bearing electron-withdrawing groups in either halides or organotin substrates gave cou...

ESI-MS based methodology for the rapid reactivity screening of [PW(11)O(39)RhCl](5-) and [PW(11)O(39)Ir(H(2)O)](4-) toward various metalation-intended substrates (reagents with an activated C-H bond, boronic acids and organotin compounds) is presented. Formation of a series of new organometallic POM derivatives with Rh-R (R = malonate, phenylacetate, CH(3), Ph, ferrocenyl) and Ir-R (R = CH(3)) ...

among the different reducing agents tributyltin hydride was found to be a powerful reducing agent for the denitration of a series of tertiary and secondary nitroesters. the organotin residues removed from the crude product using saturated potassium fluoride solution. the yield of the reactions was 62-98%.