An autoradiographic method (14C-iodoantipyrine autoradiography) was used to measure regional optic nerve blood flow (ONBF) under basal conditions in 11 adult female cats. Flow was measured in six regions of the optic nerve: (1) prelaminar, (2) laminar, (3) 1 mm post-laminar, (4) 4 mm post-laminar, (5) 6 mm post-laminar, and (6) intracranial optic nerve and chiasm. A gradient of flow rates was f...

Optic neuritis an inflammatory disorder of the optic nerve inflammation is usually in young’s with symptoms of eye pain and vision loss that occurs is a common symptom of MS. Optic neuritis is one of the first symptoms of MS that observable into disorders in white matter of cerebral cortex. The risk of MS in patients with optic neuritis during 2 years 20% in 15 years, 45-80% is calculated...

Twenty three patients with traumatic optic neuropathy were managed by medical and surgical treatment as follows. High dose intravenous steroids were initiated in all patients. If visions did not improve significantly after 24 to 48 hours decompression of an optic nerve sheath haematoma by medial orbitotomy and neurosurgical decompression of the optic canal were considered based on computed tomo...

Avulsion of the optic nerve is an infrequent traumatic event which results in a permanent and usually devastating loss of vision. We present two cases which highlight the salient features of partial and complete optic nerve avulsion. The clinical findings, including the results of B-scan ultrasonography, fluorescein angiography, and computed tomography (CT) are discussed. In addition, the past ...

INTRODUCTION EPIDEMIOLOGY PERIPHERAL NERVE ANATOMY AND PHYSIOLOGY PATHOPHYSIOLOGY OF NERVE INJURIES END ORGAN CHANGES FOLLOWING DENERVATION MECHANISMS OF NERVE INJURY ELECTRODIAGNOSIS OF PERIPHERAL NERVE INJURIES REHABILITATIVE MANAGEMENT OF PERIPHERAL NERVE INJURIES CAUSALGIA (COMPLEX REGIONAL PAIN SYNDROME, TYPE-II) UPPER EXTREMITY NERVE INJURIES AND ENTRAPMENT SYNDROMES NERVE INJURIES AND EN...

PURPOSE To determine whether inducible nitric oxide synthase (NOS-2) is involved in glaucomatous optic neuropathy. METHODS Chronic elevation of rat intraocular pressure (IOP) leading to optic nerve damage was induced by episcleral injection of hypertonic saline, which caused sclerosis and blockade of aqueous humor outflow pathways. Expression of NOS-2 in the retina and optic nerve head (ONH) ...