The multivariate calibration problem deals with inference concerning an unknown value of a covariate vector based on observation response vector. Two distinct scenarios are considered in the problem: controlled where covariates non-stochastic, and random random. Under calibration, interest is computation confidence region for that computing prediction Assuming standard normal linear regression ...

Naphthol isomers were simultaneously and spectrophotometrically determined in wastewater, using a model based on net analyte signal (NAS). The calibration method used is a variation of the original hybrid linear analysis method as proposed by Goicoechea and Olivieri (HLA/GO). Owing to spectral interferences, the simultaneous determination of mixtures of naphthol isomers, using a spectrophotomet...

The generation of particles in gas handling systems as a result of corrosion is a major concern in the microelectronics industry. The corrosion can be caused by the presence of trace quantities of water in corrosive gases such as HCl or HBr. Presently there are several commercial instruments that are capable of detecting trace water vapor with detection limits as low as 50 ppb in N2. However, n...

The simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP) mixtures in bovine milk by spectrophotometric method is, due to spectral interferences, a difficult problem in analytical chemistry. By means of multivariate calibration methods, such as partial least square (PLS) regression, it is possible to obtain a model adjusted to the concentration values of the mixtures used ...

Second-order calibration and multivariate spectroscopic-kinetic measurements in the visible region are proposed to improve the Jaffé method for creatinine assay. Analyses performed on synthetic mixtures containing bilirubin, glucose, and albumin confirm that second-order calibration is useful for creatinine determination in human serum. Quantitative determinations of creatinine with the paralle...

Resolution of binary mixtures of metoprolol and propranolol without sample pretreatment has been successfully achieved, using three different methods. The first method was based on application of Vierodt’s method that involves measurements of the absorbances at 222.6 and 213.4 nm for metoprolol and propranolol. Calibration graphs were established in the range of 1-70 μg/mL and 0.5-30 μg/mLfor m...

The UV-spectrophotometric method of analysis was proposed for simultaneous determination of fluoxetine (FLX) and sertraline (SRT). Considering the strong spectral overlap between UV-Vis spectra of these compounds, a previous separation should be carried out in order to determine them by conventional spectrophotometric techniques. Here, full-spectrum multivariate calibrations adaptive neuro-fuzz...

A rapid method for the quantitative determination of iodine value (IV) and acid value (AV) of red fruit oil (RFO) using FTIR spectroscopy and multivariate calibration of partial least square (PLS) is described. A calibration standard was developed using a series of RFO subjected to thermal treatment at without heating (ambient temperature); 100oC, 150oC, 180oC, 200oC and 300oC, respectively. Ba...