A 10-month-old male infant presented with bilateral inguinal hernia and left un-descended testis. During right herniotomy, both gonads were found on same side with mullerian duct structures. On naked eye examination, both gonads were normal looking. Excision of mullerian duct remnant and fixation of ectopic testis was made. Histopathological examination revealed that gonads were testicles. Pres...

We report a case of congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency in a Chinese genotypic male patient. Despite the male genotype, normal female external genitalia were present and with the introduction of cyclical oestrogen therapy withdrawal bleeding occurred, confirming the presence of functional endometrial tissue. We believe this to be the first report of persistent ...

Gastrointestinal endometriosis-associated malignancies are rare and diagnostically challenging. Mullerian endometrioid adenocarcinoma is the most common and likely to be confused with a primary colonic adenocarcinoma due to their overlapping histological features. We present a case of mullerian endometrioid adenocarcinoma arising from colonic endometriosis in a 61year-old woman who presented wi...

Persistent Mullerian duct syndrome is a rare form of internal male pseudohermaphroditism, in which Mullerian duct derivatives (uterus and fallopian tubes) are present in a genotypic (46XY) and phenotypic male. Over 150 cases have been reported, mainly from outside the African setting. This article presents an unexpected case encountered in an African setting. Handicaps in the management were un...

In the case reported, diagnosed with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, the presence of normal ovaries proved to be challenging to confirm due to unusual high positioned (ectopic) ovaries. MRKH syndrome is a rare pathological condition characterized by a spectrum of the Mullerian duct abnormalities resulting in congenital aplasia of the uterus and of the upper part (2/3) of the vag...

Mayer Rokitansky Kuster Houser syndrome (MRKH syndrome) is characterized by Mullerian duct structures agenesis, vaginal atresia being the commonest variant. It can be associated with renal, skeletal, spine and other malformations. Patient with Mayer Rokitansky syndrome has a varied presentation from newborn period to adolescence. Thorough investigations are required for classification of the sy...

OBJECTIVE To evaluate the change in the levels of anti-Mullerian hormone, adiponectin, weight loss and fertility parameters in obese women with or without polycystic ovary syndrome, following 12 weeks of supervised aerobic exercise. METHODS This study was conducted from August 2013 to October 2014 among obese women with or without polycystic ovary syndrome referred to Obstetrics and Gynecolog...

age at menopause using serum concentration of anti-mullerian hormone. J Clin Endocrinol Metab 2013;98:729–735. Titus S, Li F, Stobezki R, Akula K, Unsal E, Jeong K, Dickler M, Robson M, Moy F, Goswami S et al. Impairment of BRCA1-related DNA doublestrand break repair leads to ovarian aging in mice and humans. Sci Transl Med 2013;5:172ra21. Tremellen K, Savulescu J. Ovarian reserve screening: a ...

Herlyn werner wunderlich syndrome (HWWS) is a rare congenital mullerian ductal Anomaly (MDA) characterised by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It generally occurs at puberty and exhibhits non-specific and variable symptoms with acute or chronic pelvic pain shortly following menarche, causing a delay in diagnosis. Moreover, the diagnosis is com...

Adenofibroma is an extremely rare benign biphasic neoplasm that is classified into the mixed epithelial and mesenchymal tumor group. These tumors tend to occur in postmenopausal and elderly women. We report the case of a large polypoidal mass per vagina occupying the whole pelvis in a young woman. Preoperative biopsy showed benign epithelial and mullerian mesenchymal components suggestive of mu...