The growing amount of information regarding mucosal immunology in animals resulted from a need to better understand the pathogenesis of diseases entering the body through mucosa surfaces, including the respiratory tract. The second reason for such studies is associated with a search for alternative ways of vaccine application, including delivery to the mucosa of the respiratory tract. This revi...

Cystic fibrosis is a multisystemic disease with an autosomal recessive transmission, being one of the most frequent genetic affection in pediatric pathology. The disease is produced by the mutation of the gene that encodes the protein which regulates the transmembrane conductance, having a large distribution in the epithelial cells of the respiratory tract, the gastro-intestinal tract, in sweat...

In recent years, there has been a significant increase in the prevalence of diseases nose and paranasal sinuses. Inflammatory mucous membrane nasal cavities (rhinitis) are most commonly characterized as syndrome which patient experiences some combination persistent symptoms, including rhinorrhea, sneezing, congestion, itching burning cavity. Among chronic forms rhinitis, allergic rhinitis occup...

The current concepts of the pathogenesis of emphysema hold that progressive, chronic destruction of the alveolar structures occurs because there was in imbalance between the proteases and antiproteases in the lower respiratory tract. In this context, proteases, particularly neutrophil elastase, work unimpeded to destroy the alveolar structures. This concept has evolved from consideration of pat...

The relationship between exercise and susceptibility to upper respiratory tract infection (URTI) has been modelled in the form of a 'J'shaped curve as illustrated in FIGURE 1 and the relationship between exercise load and immune function is modelled as the inverse (mirror image of this curve). This model suggests that while engaging in moderate activity may enhance immune function above sedenta...