OBJECTIVES Renal damage is common in scleroderma. It can occur acutely or chronically. Renal reserve might already be impaired before it can be detected by laboratory findings. Microbubble-based contrast-enhanced ultrasound has been demonstrated to improve blood perfusion imaging in organs. Therefore, we conducted a study to assess renal perfusion in scleroderma patients utilizing this novel te...

OBJECTIVE To evaluate surfactant production and function in term neonates with transient tachypnea of the newborn (TTN). STUDY DESIGN Samples of gastric aspirates collected within 30 minutes of birth from 42 term newborns with gestational age ≥ 37 weeks (21 patients with TTN and 21 control subjects), delivered via elective cesarean delivery, were analyzed with lamellar body count and stable m...

A precise, accurate and well documented method for the sizing and counting of microbubbles is essential for all aspects of quantitative microbubble-enhanced ultrasound imaging. The efficacy of (a) electro-impedance volumetric zone sensing (ES) also called a Coulter counter/multisizer; (b) optical microscopy (OM); and (c) laser diffraction (LD), for the sizing and counting of microbubbles was as...

OBJECTIVE The purpose of the study was to explore the anti-tumor effect of ultrasound -targeted microbubble destruction mediated herpes simplex virus thymidine kinase (HSV-TK) suicide gene system on mice hepatoma. METHODS Forty mice were randomly divided into four groups after the models of subcutaneous transplantation tumors were established: (1) PBS; (2) HSV-TK (3) HSV-TK+ ultrasound (HSV-T...

Controlling states and growths of a microscale bubble (or pendant drop) in a static liquid on a solid surface (or orifice) can be achieved by introducing general dimensionless phase diagrams provided in this work. Nowadays, microbubbles are often used to control transport phenomena in various microand nano-technologies. This work parametrically presents general three-dimensional phase diagrams ...

Novel "soft" microbubbles have been fabricated to show outstanding ultrasound imaging capability, and triggered CuS nanoparticles delivery through ultrasound-targeted microbubble destruction for efficient photothermal ablation of cancer cells.

Rheumatoid arthritis (RA) is an autoimmune disease characterized by severe inflammation of the synovial tissue. Here, we assess feasibility liposome-loaded microbubbles as theranostic agents in a murine model. First, contrast-enhanced ultrasound (CEUS) was used to quantify neovascularization this model since CEUS well-established for RA diagnosis humans. Next, potential and (US) selectively enh...

Ozone was adopted to be an alternative technology for the elimination of various kinds micropollutants. However, ozonation is still limited by poor ozone dissolution in water. Microbubble proposed overcome this limitation. This paper aimed investigate effect inlet gas flow rate on production and solubility liquid phase. A double dielectric barrier discharge (DDBD) -based generator used connecte...