Currently much debate, attention and concern surrounds the use of genetically modified plants or animals. But there has not been much concern about microorganisms, although we all are aware of the place of microorganisms in the circle of life, their abundance and diversity. There are many examples regarding the application of genetically engineered microorganisms (GEMs), however, like other hig...

• The performance of 10 single or in DUOCAP® combination delivery systems was evaluated vitro SHIME model. Viability L. acidphilus and caffeine release were used as markers under fed fasted conditions. DR-in-DR DR-in-VC showed the slowest release. prevented acidophilus damage upper GIT. Delivery DUOCAP changed short chain fatty acid profile colonic Oral administration active pharmaceutical ingr...

Phosphate release from sediments hampers the remediation of aquatic systems from a eutrophic state. Microbial phosphatases in sediments release phosphorus during organic matter degradation. Despite the important role of phosphatase-expressing bacteria, the identity of these bacteria in sediments is largely unknown. We herein presented a culture-independent method to phylogenetically characteriz...

Phosphate release from sediments hampers the remediation of aquatic systems from a eutrophic state. Microbial phosphatases in sediments release phosphorus during organic matter degradation. Despite the important role of phosphatase-expressing bacteria, the identity of these bacteria in sediments is largely unknown. We herein presented a culture-independent method to phylogenetically characteriz...

Immune responses against pathogens require that microbial components promote the activation of antigen-presenting cells (APCs). Autoimmune diseases and graft rejections occur in the absence of pathogens; in these conditions, endogenous molecules, the so-called 'innate adjuvants', activate APCs. Necrotic cells contain and release innate adjuvants; necrotic cells also release high-mobility group ...

Abstract The crosstalk between the immune and neuroendocrine system is critical for intestinal homeostasis gut-brain communications. However, it remains unclear how cells participate in gut sensation of hormones release response to environmental cues, such as self microbial lipids. We show here that lipid-mediated engagement invariant natural killer T (iNKT) with enterochromaffin (EC) cells, a ...

The innate immune system plays a critical role in defense against microbial infection and employs germline-encoded pattern recognition receptors to detect broadly conserved microbial structures or activities. Pattern recognition receptors of the nucleotide binding domain/leucine rich repeat (NLR) family respond to particular microbial products or disruption of cellular physiology, and mediate t...

On Earth, marine anaerobic methane oxidation (AOM) can be driven by the microbial reduction of sulfate, iron, and manganese. Here, we have further characterized marine sediment incubations to determine if the mineral dependent methane oxidation involves similar microorganisms to those found for sulfate-dependent methane oxidation. Through FISH and FISH-SIMS analyses using 13C and 15N labeled su...

The dynamics of the nitrogen intermediates N2O and NO2 in estuarine sediments were studied along a salinity gradient in the eutrophied Weser Estuary (Germany) using microsensors for N2O, NO2, NOx, and O2. During dark incubations in the laboratory of sediment samples from a freshwater site, a brackish water site with fluctuating salinity, and a marine site, the effects of environmental changes i...