BACKGROUND The place of systemic corticosteroids in the treatment of children with chronic rhinosinusitis (CRS) remains unclear. OBJECTIVE We sought to assess the effectiveness and tolerability of oral methylprednisolone as an anti-inflammatory adjunct in the treatment of CRS in children. METHODS Forty-eight children (age, 6-17 years) with clinically and radiologically proved CRS were inclu...

this study was conducted to investigate the correlation between lipid-lowering and bone-protective effects of eicosapentaenoic acid on steroid-induced bonechanges in rats. twenty-one male 10-week-old wistar rats were divided into 3 groups (n = 7 each) and treated with 0.9% nacl sc (group 1) or methylprednisolone 7 mg/kg sc once a week (group 2) or methylprednisolone 7 mg/kg sc once a week + eic...

Abstract Cutaneous arteritis (CA) is a rare limited form of polyarteritis nodosa (PAN), which usually has benign prognosis and requires less aggressive therapy. Here, we present case CA localized to both skin muscle the same area as lesions. We propose with disorders severe subtype literature review disorders, may require treatment intravenous pulse methylprednisolone, immunosuppressive therapy...

BACKGROUND To determine whether hCG ratio at 48 h can predict ultimate viability of intrauterine pregnancies of uncertain viability (IPUVs) in the pregnancy of unknown location (PUL) population. METHODS Prospective observational study from June 2001 to October 2004. All women classified with PUL had serum hCG levels measured at 0 and 48 h to calculate hCG ratio (hCG 48/hCG 0 h). All women wer...

BACKGROUND Febrile infections are an important cause of paediatric refractory status epilepticus, and immune-mediated mechanisms and inflammatory processes have been associated with neurological manifestations in such patients. The aim of this study was to investigate the effects of immunotherapy as adjuvant treatment for febrile refractory status epilepticus. METHODS We retrospectively revie...

We report the case of a 36-year-old woman who presented with headache, fever, and amenorrhea. Laboratory analysis revealed hypopituitarism and autoimmune thyroiditis, while a cerebrospinal fluid study suggested concurrent aseptic meningitis. A magnetic resonance image (MRI) scan revealed a 1.0×0.9 cm cystic mass enlarging the sella turcica. Surgical resection via an endoscopic transsphenoidal r...