Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

Radiation dosimetry by Fricke gel was largely used, generally focused and optimized for radiotherapy applications therefore involving relative high dose levels. Fricke gel dosimetry has several advantages, like dose rate and LET almost independence, 3D mapping, among other. This work presents a novel Fricke gel dosimeter optimized for low dose levels. Several chemical composition were studied v...

The BANG (MGS Research Inc., Guilford, CT) polymer gel has been used as a dosimeter to determine the three-dimensional (3D) dose distribution of a ruthenium-106 (Ru-106) ophthalmologic applicator. An eye phantom made of the BANG gel was irradiated with the Ru-106 source for up to 1 h. The phantom and a set of calibration vials were scanned simultaneously in a GE 1.5 T MR imager using the Hahn s...

Fricke-gel layer dosimeters (FGLD) and Fricke gel dosimetric catheters (FGDC) have been designed and tested with the aim of enquiring their suitability for HDR Ir brachytherapy source control and for in-vivo dose verification during treatment. Anisotropy function measurements have been carried out with FGLDs in which a thin plastic tube has been placed in for the Ir source insertion. FGDCs are ...

Introduction: Different dosimetric modalities (e.g., ionization chambers, semiconductors, TLDs, radiographic films) often have some problems determining isodose curves and percentage depth doses in high dose gradient regions. Research has been ongoing to develop portable high resolution dosimetry devices with accurate absolute dosimetry capabilities and easy data analysis. The ‘PRESAGE’ dosimet...