Comparison Of Levobupivacaine And Clonidine With Bupivacaine And Clonidine In Spinal anaesthesia ForLowerSegmentCaesareanSection Introduction: Intrathecal LevoBupivacaine is having similar clinical profile with less cardio-toxicity than Bupivacaine is used commonly for LSCS. Clonidine as an additive to LA provides effective, prolonged and dose dependent analgesia. In this study we compared effe...

Backgrounds and objectives: This an attempt to compare the effects of 15ml levobupivacaine 0.75%, 20 ml 0.375% 30ml 0.25% with fixed dosage (75mg) on block characteristics in upper limb surgeries using ultrasound guided supraclavicular block. Materials methods: Titled “Comparative study three different volumes concentrations Levobupivacaine block” performed Department Anaesthesiology, Chettinad...

Materials and methods: Forty consenting patients undergoing unilateral total knee arthroplasty were included in this prospective randomized study. Spinal anesthesia was achieved with 15 mg plain bupivacaine at the L3-4 or L4-5 interspace. After resolution of the spinal anesthesia, patients were randomized into 2 groups: “3-in-1” femoral nerve blocks were performed using 30 mL of 0.25% levobupiv...

Spinal anesthesia is the most popular regional anesthesia technique for cesarean delivery as it is easily performed and provides rapid onset of block followed by dense surgical anesthesia. Although bupivacaine seems to be widely and routinely used long acting amide type local anesthetic drug for spinal anesthesia, ropivacaine and levobupivacaine may occasionally be chosen. However, it is diffic...

Isobaric levobupivacaine is a long acting amide type of local anaesthetic that S-enantiomer racemic bupivacaine with clinical profile resembling bupivacaine. It has been stated its faster protein binding rate reflects decreased degree toxicity and studies done have supported it lesser cardiovascular central nervous system than Sixty patients aged between 18yrs 60yrs physical status ASA grade 1 ...

OBJECTIVE Post-tonsillectomy pain is believed to be mediated by noxious stimulation of C-fiber afferents located in the peritonsillary space, and local anesthetic infiltration to this area may decrease pain by blocking the sensory pathways and thus preventing the nociceptive impulses. We aimed to compare the effects of different concentrations of preincisional peritonsillar levobupivacaine (0.2...

PURPOSE Intravenous lipid emulsions have been used to treat the systemic toxicity of local anesthetics. The goal of this in vitro study was to examine the effects of lipid emulsions on the norepinephrine-mediated reversal of vasodilation induced by high doses of levobupivacaine, ropivacaine, and mepivacaine in isolated endothelium-denuded rat aorta, and to determine whether such effects are ass...

Background: Local analgesia technique has important advantages to manage postoperative pain; however, the duration of pain relief is relatively short due to the pharmacological characteristic of local anesthetics. Hence, in the current study, we planned to explore the hypothesis that adding dexmedetomidine to levobupivacaine in transversus abdominis plane (TAP) block prolongs the duration of an...

BACKGROUND AND OBJECTIVES The study of the vasomotor effect of local anesthetics (LA) is of paramount importance for the analysis of the occurrence of cardiotoxic and neurotoxic effects, and drug interactions. In order to find a safer drug than racemic bupivacaine, this study aimed to analyze digital infrared imaging of acute vasomotor effect of bupivacaine and levobupivacaine in rats intraperi...