نتایج جستجو برای: ketone bodies

تعداد نتایج: 91778  

Journal: :Folia Endocrinologica Japonica 1988

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Journal: :Journal of Neurochemistry 2012

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Journal: :American journal of physiology. Endocrinology and metabolism 2011
Dongjuan Zhang Hang Yang Xiaomu Kong Kang Wang Xuan Mao Xianzhong Yan Yuan Wang Siqi Liu Xiaoyan Zhang Jing Li Lihong Chen Jing Wu Mingfen Wei Jichun Yang Youfei Guan

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. To date, the molecular mechanisms of DN remain largely unclear. The present study aimed to identify and characterize novel proteins involved in the development of DN by a proteomic approach. Proteomic analysis revealed that 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase 2 (HMGCS2), the key enzyme in ketogenesis, was i...

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Journal: :Stroke 1992
J Lundgren M L Smith A M Mans B K Siesjö

BACKGROUND AND PURPOSE Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage after brain ischemia and causes fatal postischemic seizures, probably by incre...

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Journal: :The Journal of reproduction and development 2009
Shuichi Matsuyama Satoshi Ohkura Kinuyo Iwata Yoshihisa Uenoyama Hiroko Tsukamura Kei-Ichiro Maeda Koji Kimura

Ketone bodies are considered to act as a signal to suppress gonadotropin release during negative energy balance. The present study examined the effect of 48-h fasting on the mRNA expressions of monocarboxylate transporter 1 (MCT1) and MCT2, which are involved in ketone body transport, in several brain regions. Quantitative real-time RT-PCR analysis showed that the MCT2 mRNA levels were signific...

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2015
Candida J. Rebello Jeffrey N. Keller Ann G. Liu William D. Johnson Frank L. Greenway

BACKGROUND Impaired brain glucose metabolism appears to be a potential pathogenic feature of mild cognitive impairment (MCI). This study examined the potential for increasing circulating ketone bodies through medium chain triglyceride (MCT) supplementation, as a means to beneficially modulate brain homeostasis in subjects with MCI. METHODS Six participants with MCI were enrolled in a randomiz...

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Journal: :The American journal of physiology 1975
A Gjedde C Crone

Fed and starved rats were studied on successive days during a 5-day starvation period. The ability of ketone bodies to pass the blood-brain barrier was estimated by single common carotid injections of labeled ketone bodies and water, and results were expressed as the ratio between the normalized activities of tracers in tissue and blood, the brain uptake index (BUI). BUI of D-3-hydroxybutyrate ...

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Journal: :Journal of Clinical Investigation 1992

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Journal: :FEBS Letters 1970

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Journal: :Cardiovascular Research 2017

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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