Clinical Features (Fig. 1, overleaf) The condition appears to be asymptomatic and presents as a chance clinical finding. The corneal lesions are round, discrete dense opacities 0 5 mm. or less in diameter. They lie at the level of Bowman's membrane and usually extend just into the superficial stroma. The typical lesion has a striking white or creamy, rather porous-looking centre, and this is su...

Tamoxifen citrate (ICI46474) is an antiestrogenic agent used in cases of disseminated breast carcinomas and as adjuvant postoperative therapy. Toxic reactions to tamoxifen, such as decreased visual acuity, bilateral macular edema, and yellow-white dots in the paramacular and foveal areas, are relatively rare (reported incidence between 0.9%-12%). In 1978, Kaiser-Kupfer and Lippman first reporte...

I read with interest the two case reports by Kwon et al. on ‘‘New Treatment for Band Keratopathy: Superficial lamellar Keratectomy, EDTA Chelation and Amniotic Membrane Transplantation’’ (1). In their article, they describe two cases of calcific band keratopathy (CBK) that were treated with a combination of EDTA chelation, superficial keratectomy and amniotic membrane transplantation. The autho...

AIMS This study was designed to investigate the therapeutic potential of excimer laser for recurrent painful erosions in patients not suited to treatment with penetrating keratoplasty. METHODS Phototherapeutic keratectomy (PTK) with the excimer laser was performed prospectively on a series of 13 eyes of 12 patients with recurrent corneal erosions in connection with bullous keratopathy of vari...

Graves' disease is a self-limiting autoimmune thyroid disorder caused by stimulating antibodies to the thyroid-stimulating hormone receptor. It usually affects middle-aged females in fourth sixth decade of life. distinguished keratopathy, chemosis, proptosis, and eyelid swelling, addition ocular discomfort. A total 3-5% cases present with severe form orbitopathy, which manifests diminution visi...