INTRALESIONAL HYALURONIDASE WITH TRIAMCINOLONE FOR RECALCITRANT PRETIBIAL MYXEDEMA Abstract Pretibial myxedema resulting in progressively worsening cutaneous induration and expanding nodules can lead to pain, discomfort and functional impairment. Treatment of resistant lesions presents a special challenge whereby topical therapies are insufficient, and systemic therapies are met with poor toler...

Intralesional sclerotherapy as a primary modality of management for cystic hygroma is successfully described in literature. It has many benefits over surgical approach; recurrence being the concern of as much as 20% of patients in which apparent complete excision has been performed. Bleomycin is one of sclerosing agents used as intralesional therapy in cystic hygroma. Complete response usually ...

EGFR: epidermal growth factor receptor NSCLC: nonesmall cell lung cancer INTRODUCTION Both scarring and nonscarring alopecias have been described with the long-term use of epidermal growth factor receptor (EGFR) inhibitors. Current treatments revolve around anti-inflammatory agents such as topical corticosteroid ointments, creams, and intralesional injections to reduce follicular inflammation. ...

Central giant cell granuloma (CGCG), an infrequent disease, is a non-neoplastic bone lesion. Clinically, it may be asymptomatic or show aggressive and painful condition that can cause root resorption, cortical destruction. The aim of this report to emphasize the importance intralesional corticosteroid injection, which less invasive technique in treatment CGCG. 24 years old female patient came o...

The presence of intralesional natural regulatory T cells, characterized by the expression of Foxp3 mRNA, was analyzed in patients with localized leishmaniasis due to Leishmania guyanensis infection that was unresponsive to treatment with pentamidine isethionate. Foxp3 mRNA levels were associated with unresponsiveness to treatment among patients with a lesion duration of 1 month, but this associ...

Cutaneous changes after local corticosteroid administration may include dermal atrophy, hyperpigmentation, alopecia, and hypopigmentation. Linear hypopigmentation and atrophy after intralesional injection of triamcinolone acetonide has been reported in the literature as a very rare side effect. A 30-year-old woman visited our dermatology department for a linear hypopigmented patch with atrophy ...

Tuen Mun Social Hygiene Clinic, 5/F Tuen Mun Eye Centre, 4 Tuen Lee Street, Tuen Mun, N.T., Hong Kong Treatment of keloids is difficult and the response to first line treatment including silicone gel sheet, compression, topical and intralesional steroid are variable. Intralesional cryosurgery (ILC) may be useful for treating some earlobe keloids not responsive to these first line treatments. IL...

INTRODUCTION: Many studies have proved the role, efficacy and safety profile of intralesional bleomycin in the management of hypertrophic scars and keloids.1 Liposomes, by virtue of their lipid bilayer, have potential to enhance the delivery of drug to the desired area. Drugs encapsulated in liposomes are expected to be transported without rapid degradation and minimum side effects to the recip...