OBJECTIVE We aimed at detecting neurophysiological changes, in the primary motor tongue representation in adults with persistent stuttering. METHODS Using transcranial magnetic stimulation in 12 patients and 14 controls, we examined motor threshold, motor-evoked potential (MEP) input-output curve, short-term intracortical inhibition (SICI) and intracortical facilitation (ICF), based on eight ...

There are increasing studies indicating neuroprotective effects for vitamin B12. In the present study, the effect of intracortical microinjection of vitamin B12 was investigated on penicillin-induced epileptiform activity. We also examined the effects of intracortical microinjection of diazepam (a GABA-benzodiazepine receptor agonist) and flumazenil (a GABAbenzodiazepine receptor antagonist) to...

PURPOSE The aim of this study was evaluate the morbidity after anterior iliac crest bone harvesting by comparison of 2 approaches: medial and intracortical. PATIENTS AND METHODS Between April 2006 and February 2010, 73 consecutive subjects underwent anterior iliac crest bone harvesting. The sample was divided in 2 groups: 37 subjects treated with the medial approach and 36 with the intracorti...

OBJECTIVE Neural prostheses, or brain-machine interfaces, aim to restore efficient communication and movement ability to those suffering from paralysis. A major challenge these systems face is robust performance, particularly with aging signal sources. The aim in this study was to develop a neural prosthesis that could sustain high performance in spite of signal instability while still minimizi...