نتایج جستجو برای: immune mediated disease

تعداد نتایج: 2013882  

Journal: :Biomedical Journal of Scientific and Technical Research 2023

IgG4-related disease (IgG4-RD) is a rare immune-mediated condition associated with fibro-inflammatory lesions. It was first recognized as distinct in 2003 [1,2]. of middleaged patients, mean age at diagnosis approximately 60 years old that predominates men [1]. often presents multiorgan occurring synchronous or metachronous fashion tendency to form tumor-like lesions almost every organ system

Farzaneh Pourasgari Fatemeh Rahbarizadeh Fereidoun Mahboudi, Hamidreza Korram Khorshid Haydeh Darabi Kayhan Azadmanesh Masoumeh Ebtekar, Mehdi Mahdavi Zuhair Mohammad Hassan

Background: Cell mediated immunity, especially cytotoxic T cell responses against HIV-1 infection, plays a critical role in controlling viral replication and disease progres-sion. DNA vaccine is a novel technology which is known to stimulate strong cellular immune responses. Many DNA vaccines have been tested for HIV infection but there is still no effective vaccine against this infection. Cons...

2017
Kadri Haller-Kikkatalo Kristi Alnek Andres Metspalu Evelin Mihailov Kaja Metsküla Kalle Kisand Heti Pisarev Andres Salumets Raivo Uibo

The presence of autoantibodies usually precedes autoimmune disease, but is sometimes considered an incidental finding with no clinical relevance. The prevalence of immune-mediated diseases was studied in a group of individuals from the Estonian Genome Project (n = 51,862), and 6 clinically significant autoantibodies were detected in a subgroup of 994 (auto)immune-mediated disease-free individua...

Journal: :Journal of Immunology 2023

Abstract Dysregulated humoral immune mechanisms result in immunoglobulin production that is pathogenic and contributes to a wide range of autoimmune diseases transplant rejection. Proteases derived from human pathogens can specifically cleave these immunoglobulins (Ig) potentially eliminate circulating, cell-surface immune-complex Ig classes modulate Ig-mediated autoimmunity inflammation, provi...

Journal: :Clinical and Experimental Obstetrics & Gynecology 2023

Objectives: Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disease characterized by thrombocytopenia. This review will examine the Notch-aromatic hydrocarbon receptor (AhR)-interleukin-22 (IL-22) signaling pathway regulatory mechanisms in ITP to generate ideas for pathogenesis and etiological investigation of disease. Mechanism: Studies had shown that abnormal imbalance immune...

Journal: :مجله علوم اعصاب شفای خاتم 0
mokhtar ahmadi islamic azad university, mashhad branch, mashhad, iran hossein feizi islamic azad university, mashhad branch, mashhad, iran fatemeh shahbeigi islamic azad university, mashhad branch, mashhad, iran

multiple sclerosis (ms) is a neuroinflammatory autoimmune disease which mediated by various molecular and cellular immune components however recent reports have shown that coagulation factors that traditionally separate from the immune system might also be involved in ms development and progression.studies on experimental autoimmune encephalomyelitis (eae) and human ms patients reports alterati...

Journal: :iranian journal of allergy, asthma and immunology 0
gholamreza azizi imam hassan mojtaba hospital, alborz university of medical sciences, karaj, iran. mohsen reza haidari department of neurology, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran. mohammadreza khorramizadeh department of immunology, school of public health, tehran university of medical sciences, tehran, iran. fatemeh naddafi department of immunology, school of public health, tehran university of medical sciences, tehran, iran. fatemeh. reza sadria department of immunology, school of public health, tehran university of medical sciences, tehran, iran. mohammad hassan javanbakht department of immunology, school of public health, tehran university of medical sciences, tehran, iran.

experimental  autoimmune  encephalomyelitis (eae)  is  a  mouse  model  for  multiple sclerosis (ms), this autoimmune disease is mainly mediated by adaptive and innate immune responses that lead to an inflammatory demyelination and axonal damage. imatinib mesylate is a  selective protein  tyrosine kinase inhibitor  with immunomodulatory  properties  that abrogates multiple signal transduction p...

H. Aghapour Kazemi N. Mosleh T. Shomali,

Zataria multiflora essential oil possesses immunomodulatory effects and the present study investigatesits effect on immune responses to live Newcastle disease (ND) vaccines and faecal shedding period ofvaccine strain virus in chickens. One hundred and eighty chickens from both sexes were divided into 6 equalgroups: group 1: unvaccinated, group 2: vaccinated (B1 vaccine followed by La Sota 10 da...

Journal: :jundishapur journal of microbiology 0
abdolhossein dalimi parasitology department, faculty of medical sciences faculty, tarbiat modares university, tehran, ir iran; abdolhossein dalimi dvm, phd, professor, department of parasitology, faculty of medical sciences, tarbiat modares university, p.o.box:14155-331, tehran, ir iran vahid nasiri parasitology department, razi vaccine and serum research institute, karaj, ir iran

conclusions in conclusion, pegfp-kmp-gp96 (fusion) induced th1 platform immune response against leishmania major (mrho/ir/75/er) infection. results according to the results, the level of cytokines interferon-gamma (ifn-γ) and interleukin (il)-4, and ratio of ifn-γ /il4 was changed among different groups of mice before and seven weeks after immunization. the cytokines were increased significantl...

Journal: :jundishapur journal of microbiology 0
alireza rafiei molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran abolghasem ajami molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran araz mohammad mirabi department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran; department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran. tel: +98-1133543614 mohammad jafar saffar department of infectious diseases, buali hospital, faculty of medicine, mazandaran university of medical sciences, sari, ir iran omolbanin amjadi molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran mohammad reza haghshenas molecular and cell biology research center, department of microbiology and virology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran

conclusions acute hev infection shows a pattern of th1-type immune response, and the direct significant positive correlation between the serum level of scd26 and ifn-γ in acute hev infected patients, suggests that the trend of scd26 levels is a valuable marker for predicting hepatic inflammation in hepatitis e. results the results showed a significant difference in ifn-γ and scd26 (p < 0.0001 a...

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