Hypokalemia is a common electrolyte abnormality often encountered in daily practice. While mild hypokalemia asymptomatic, moderate-to-severe usually manifested as significant symptoms such muscle weakness. In this paper, we presented case of 23-years-old male coming to our emergency department because weakness all his four limbs when he woke up the morning. Physical examinations were within nor...

Hypokalemic periodic paralysis (HypoPP) is an autosomal dominant disorder characterized by episodic attacks of muscle weakness associated with a decrease in blood potassium levels. Recently, mutations in the gene coding for the skeletal muscle voltage-gated sodium channel alpha subunit (SCN4A) have been reported. We detected the R672H mutation in one HypoPP Turkish family.

Cliff W. Hampton, Joseph R. Sweigart, Susan M. Nikels, Michael Hanley 1 Internal Medicine, University of Colorado Denver, Aurora, CO, United States. 2 Pulmonary Sciences & Critical Care Medicine, University of Colorado Denver, Aurora, CO, United States. (Control ID: 1327979) Learning Objective 1: Recognize thyrotoxic periodic paralysis as an uncommon complication of thyrotoxicosis Learning Obje...

Unilateral vocal fold paralysis is a common clinical problem which frequently causes severe dysphonia. Various treatment options exist for this condition, with the type I thyroplasty being one of the more commonly performed surgical procedures for vocal rehabilitation. The Voice-Related Quality of Life (V-RQOL) Measure is a validated outcomes instrument for voice disorders. This study measured ...

9. Fontaine B, Khurana TS, Hoffman EP et al. Hyperkalemic periodic paralysis and the adult muscle sodium channel alpha-subunit gene. Science 1990; 250: 1000–1002 10. Ptacek LJ, George AL Jr, Griggs RC et al. Identification of a mutation in the gene causing hyperkalemic periodic paralysis. Cell 1991; 67: 1021–1027 11. Rojas CV, Wang JZ, Schwartz LS et al. A Met-to-Val mutation in the skeletal mu...

Hypokalemic Periodic Paralysis (HPP) may occur as a rare complication of Sjogren Syndrome (SS) and Renal Tubular Acidosis (RTA). A 64-year male patient came with HPP, and was later diagnosed with distal RTA. The patient, who had no xerostomia and xerophthalmia, was diagnosed with primary SS from serologic and histologic findings of minor salivary gland biopsy. The patient recovered after potass...