BACKGROUND Real-world data on the benefit/risk profile of medicines is needed, particularly in patients who are ineligible for randomised controlled trials conducted for registration purposes. This paper describes the methodology and source data verification which enables the conduct of pre-licensing clinical trials of COPD and asthma in the community using the electronic medical record (EMR), ...

This paper presents an interdisciplinary scenario analysis to assess the influence of global and regional change on future water availability and water consumption in the Upper Ouémé catchment in central Benin. For the region three development scenarios were evolved. These scenarios are combined with climate change scenarios based on the IPCC (Intergovernmental Panel on Climate Change). In the ...

Abstract Background The 2020 treatment guidelines for patients diagnosed with nontuberculous mycobacterial lung disease (NTMLD) recommend antibiotic initiation rather than “watchful waiting” most patients. Little is known regarding how delayed (DT) may impact healthcare resource utilization (HRU). goal of this study was to assess HRU early (ET) or DT in NTMLD. Methods We conducted a retrospecti...

This research focuses on predicting the streamflow of Anai-weir catchment using SWAT (Soil and Water Assessment Tools) Mock models. The studied is approximately 34,024 ha wide. rainfall climatological data were collected from three nearest stations, namely Kandang IV (13.8 km far), Kasang (15.2 Sicincin Stations (11.2 2010 to 2019. first methodology delineate catchment, form a Hydrologic Respon...

The continuous growth of irrigated agricultural has resulted in decline groundwater levels many regions Maryland and the Mid–Atlantic. main objective this study was to use crop water productivity as an index evaluate different irrigation strategies including rainfed, groundwater, recycled use. Soil Water Assessment Tool (SWAT) used simulate watershed hydrology yield. It estimate corn soybean us...

The growing expansion of socioeconomic activities without considering the potentialities and limitations regarding land use constitutes a potential source deterioration environment. present work aimed to diagnose areas conflict in municipality Batatais-SP. methodological procedure consisted geographic information systems remote sensing techniques. municipal area was regionalized into hydrologic...