tolterodine tartrate, is a new, potent and competitive muscarinic receptor antagonist in clinical development for the treatment of urge incontinence and other symptoms of unstable bladder. the purpose of this study is to establish a reliable and quick method for the assignment of tolterodine tartrate by high performance liquid chromatography with ultraviolet detection (hplc-uv). a rapid and sen...

Hypertension is one of the most common causes of death, a complex and incompletely controlled disease for millions of patients. Metoprolol, bisoprolol, nebivolol and atenolol are selective beta-blockers frequently used in the management of arterial hypertension, alone or in fixed combination with other substances. This study presents the most used analytical methods for simultaneous determinati...

Background: Artemisia dracunculus L. belongs to the Anthemideae tribe of Asteraceae family. This plant has been used in traditional folk medicine. Also, it's anti-bacterial, anti-fungal, antioxidant, anti-inflammatory and hepatoprotective activity has been proved. Objective: The purpose of this study was to evaluate the antioxidant activity of leaves and inflorescence of A. dracunculus and als...

Cloud point extraction (CPE) as a rapid, simple and efficient method coupled with high performance liquid chromatography (HPLC) was used for sample preparation and subsequent determination of carbazole, trinitrocarbazole (TrNC) and tetra nitro carbazole (TNC) in water samples. Some effective parameters on extraction, such as volume of Triton X-100, extraction time, extraction temperature, ionic...

Nicorandil is a potent drug with a dual mechanism of action which results in its wide application in treating angina patients. Since the literature review showed no single preparative method for isolation and liquid chromatography-mass spectrometry (LC-MS) compatible [high-performance liquid chromatography (HPLC) or ultra performance liquid chromatography (UPLC)] method for identification for t...

A comparison of two RP-high-performance liquid chromatography (HPLC) methods to determine efficient sample extraction to determine efficient method for getting optimum retention time and recovery of verapamil from rat plasma.

Oligonucleotides containing a biotin functionality were successfully labelled with a streptavidin nanogold conjugate and subsequently separated and analysed by high performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

in this study, for the analysis of human urine samples, a novel method explained for the determination of celecoxib, a nonsteroidal anti-inflammatory drug (nsaid), using molecularly imprinted solid-phase extraction (mispe) coupled with high-performance liquid chromatography (hplc). the synthesis of the mip was performed by precipitation polymerization in methacrylic acid (maa), ethylene glycol ...

a solid phase extraction sorbent based on polyaniline/graphene nanocomposite is presented. the structure and morphology of synthesized nanocomposite were investigated by fourier transform infrared spectroscopy, field emission scanning electron microscopy, x-ray diffraction and thermal gravimetric analysis. the dispersive solid phase extraction was employed to the isolation and preconcentration ...

High-performance liquid chromatography (HPLC) is the most versatile of the chromatographic techniques because it is applicable to a wide variety of analytes. Unfortunately, liquid mobile phases have relatively low diffusivities. A novel approach is presented for increasing the diffusivity of a liquid mobile phase. The method advocated in this study is the first process that has been described b...