نتایج جستجو برای: hematological toxicities
تعداد نتایج: 51579 فیلتر نتایج به سال:
A Phase I study was performed to determine the maximum tolerated dose (MTD), toxicities, and pharmacokinetic profile of irinotecan (CPT-11) and its active metabolites when given on a once-every-3-week schedule. Thirty-four patients with advanced refractory solid malignancies were treated with CPT-11 (240-340 mg/m2) administered as a 90-min i.v. infusion every 3 weeks. Patients were divided into...
The aim of the work is to study phytochemical composition and acute subacute toxicities aqueous extract leaves Vernonia colorata (AEVC). toxicity was performed by administering a single oral dose AEVC 5000 mg/kg body weight (bw) female Wistar rats. For study, treatments were administered orally for 28 consecutive days. control group received distilled water (10 bw). test groups doses 100, 500 1...
Breast cancer patients undergoing chemotherapy often reported side effects, including fatigue, nausea, vomiting, and unintentional weight loss. Change in body composition, especially decreased muscle mass is known to have important impact of anticancer drug toxicity. Currently, there still limited data regarding this issue. The aim the study was know relationship between low (LMM) toxicity brea...
cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...
PURPOSE There is no effective treatment for patients with advanced gastric cancer having failed to respond to first line chemotherapy. The aim of this study was to evaluate the therapeutic activity, and safety, of a FEP regimen in patients with a recurrence of, or metastatic, gastric cancer that had been unresponsive to primary chemotherapy. MATERIALS AND METHODS Recurred or metastatic gastri...
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