Ovulation Induction and Oocyte Recovery Ovarian hyperstimulation was achieved using GnRH analogue (nafarelin acetate, Synarel®, Pfizer) along with human recombinant FSH (r-hFSH: Gonal-F®, MerckSerono) in a long down-regulation protocol. Starting gonadotrophin dose varied from 150-300 IU and was based on female age, body mass index, ovarian volume, basal FSH levels and the number of preantral fo...

BACKGROUND The purpose of this study was to evaluate the efficacy and safety of nafarelin, a gonadotropin-releasing hormone (GnRH) analogue, versus danazol in the treatment of women with endometriosis in Taiwan. METHODS Fifty-nine women with laparoscopically and pathologically confirmed endometriosis were randomized to receive nafarelin or danazol for 180 days. Efficacy was assessed from mean...

We report a recently observed case of primary umbilical endometriosis without previous pelvic surgery. A 41-year-old Japanese woman complained of umbilical nodular tumor. Histopathology revealed endometriosis of an approximate 10 mm resected mass. The stromal cells in endometriosis were immunohistochemically positive for CD10. Two months later the first umbilical surgery, she underwent a left s...

BACKGROUND Women with endometriosis often experience gastrointestinal symptoms. Gonadotropin-releasing hormone (GnRH) analogs are used to treat endometriosis; however, some patients develop gastrointestinal dysmotility following this treatment. The aims of the present study were to investigate gastrointestinal symptoms among patients with endometriosis and to examine whether symptoms were assoc...

Background and Objective: Ineffective estrus detection is the foremost limiting factor in the fertility of farmed cattle worldwide. Therefore, this study investigates the effect of three synchronization protocols with Fixed Time Artificial Insemination (FTAI) on the pregnancy rate of crossbred dairy cows. Methodology: Ninety one cows were assigned to four groups where the Body Condition Score (...

Gonadotropin releasing hormone analogues (GnRHa) are often used to regress endometriosis implants and prevent premature luteinizing hormone surges in women undergoing controlled ovarian stimulation. In addition to GnRH central action, the expression of GnRH and receptors in the endometrium implies an autocrine/paracrine role for GnRH and an additional site of action for GnRHa. To further examin...