نتایج جستجو برای: glipizide
تعداد نتایج: 326 فیلتر نتایج به سال:
The two most prevalent causes of end-stage renal disease nowadays are thought to be diabetic mellitus (DM) and hypertension (ESRD). In addition discussing the function DM in ESRD, this study reviews glucose metabolism treatment hyperglycemia these patients. Although strict glycemic control ESRD patient survival were not significantly correlated numerous big trials, it is advised that prioritise...
AIM To compare the efficacy, safety and tolerability of adding rosiglitazone (RSG) vs. sulphonylurea (SU) dose escalation in older type 2 diabetes mellitus (T2DM) patients inadequately controlled on SU therapy. METHODS A total of 227 T2DM patients from 48 centres in the USA and Canada, aged > or =60 years, were randomized to receive RSG (4 mg) or placebo once daily in combination with glipizi...
BACKGROUND The optimum oral pharmacological treatment of diabetes mellitus to reduce cardiovascular disease and mortality following myocardial infarction has not been established. We therefore set out to investigate the association between individual oral glucose-lowering drugs and cardiovascular outcomes following myocardial infarction in patients with diabetes mellitus not treated with emerge...
Hypoglycemic sulfonylureas (e.g., glibenclamide, glipizide, and tolbutamide) exert their stimulatory effect on excitatory cells by closure of ATP-sensitive potassium (KATP) channels. These channels are heteromultimers composed with a 4:4 stoichiometry of an inwardly rectifying K+ channel (KIR) subunit 6.x plus a sulfonylurea receptor (SUR). SUR1/KIR6.2 reconstitutes the neuronal/pancreatic beta...
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