نتایج جستجو برای: genomic scan

تعداد نتایج: 195881  

Journal: :Proceedings of the National Academy of Sciences 2000

2013
Tadasu Nozaki Kazunari Kaizu Chan-Gi Pack Sachiko Tamura Tomomi Tani Saera Hihara Takeharu Nagai Koichi Takahashi Kazuhiro Maeshima

Genomic DNA is organized three dimensionally within cells as chromatin and is searched and read by various proteins by an unknown mechanism; this mediates diverse cell functions. Recently, several pieces of evidence, including our cryomicroscopy and synchrotron X-ray scattering analyses, have demonstrated that chromatin consists of irregularly folded nucleosome fibers without a 30-nm chromatin ...

Journal: :American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008
Kaixin Zhou Astrid Dempfle Mauricio Arcos-Burgos Steven C Bakker Tobias Banaschewski Joseph Biederman Jan Buitelaar F Xavier Castellanos Alysa Doyle Richard P Ebstein Jenny Ekholm Paola Forabosco Barbara Franke Christine Freitag Susann Friedel Michael Gill Johannes Hebebrand Anke Hinney Christian Jacob Klaus Peter Lesch Sandra K Loo Francisco Lopera James T McCracken James J McGough Jobst Meyer Eric Mick Ana Miranda Maximilian Muenke Fernando Mulas Stanley F Nelson T Trang Nguyen Robert D Oades Matthew N Ogdie Juan David Palacio David Pineda Andreas Reif Tobias J Renner Herbert Roeyers Marcel Romanos Aribert Rothenberger Helmut Schäfer Joseph Sergeant Richard J Sinke Susan L Smalley Edmund Sonuga-Barke Hans-Christoph Steinhausen Emma van der Meulen Susanne Walitza Andreas Warnke Cathryn M Lewis Stephen V Faraone Philip Asherson

Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gat...

1971

concrete labyrinths of the new social work depart-ments?where the central heating automatically goes on on October 1st and automatically goes off on April 1st, whatever the weather?the filing clerks excitedly cried: 'Isn't it amazing to have the windows open in February!' Nervous daffodils appeared on the typists' desks. It was a mild winter. Of course there were one or two contretemps. During ...

1972
Dymphna

By the time these words appear in print, I understand that we shall have taken one more step, whatever that is, towards joining the European Community whatever that is. (We have trouble enough defining what we mean by a community even within Britain; I can't imagine it's going to be any easier, in European terms, even to perceive the community, let alone define it.) Anyway, before very long, pe...

1972
Dymphna

I have recently been renewing my acquaintance with Rudyard Kipling Rudyard Kipling the poet, that is, as distinct from Rudyard Kipling the short-story writer and part-time novelist. R.K. the poet is very much out of favour at present, and has been these twenty years. I suppose this disfavour springs from his identification with the spirit of Empire, with the Raj, with the Great White Sahib, wit...

1971
Dymphna

A personal view of the social services.

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