Stomal Ulceration Stomal ulceration may follow anastomosis of the stomach to any other part of the alimentary canal. I have indicated in my first lecture that by I954, stomal ulceration had followed in over 50 per cent. of the cases in which I had carried out a gastrojejunostomy for duodenal ulcer in I943. In such cases at the second operation, the duodenal ulcer, although often reported as act...

circadian rhythms are driven by endogenous clock gene and affects in several gastric parameters causing ulcerogenesis. the study was aimed to evaluate the time dependent antiulcer activity of hydroxyzine in cold-stress-induced ulcer model. the ulcer protection effect of hydroxyzine was studied at various time intervals (9 am, 1 pm, 5 pm, 91 pm, 1 am and 5 am) in cold stress ulcer model using wi...

This study aimed to investigate the possible gastroprotective effect of tocotrienol against water-immersion restraint stress (WIRS) induced gastric ulcers in rats by measuring its effect on gastric mucosal nitric oxide (NO), oxidative stress, and inflammatory biomarkers. Twenty-eight male Wistar rats were randomly assigned to four groups of seven rats. The two control groups were administered v...

the aim of the study was to study the anti-ulcer activity of the methanolic extract of the leaves of capparis zeylanica linn on experimental animal models. the methanol extract of capparis zeylanica linn. leaves was investigated for anti-ulcer activity against aspirin plus pylorus ligation induced gastric ulcer in rats. hcl-ethanol induced ulcer in mice and indomethacin induced ulcer in rats at...

500 cases of Esophago-Gastroscopy were evaluated at the Shahid Moddares teaching and research medical center. Endoscopic diagnosis were:  38% Gastritis, 24% Duodenal Ulcer, 8% Esophageal Carcinoma, 6% Gastric Carcinoma, 6% Gastric Ulcer, 6% Hiatal Hernia, 3% Esophageal Varises.  In 68% of these cases Gastroscopy findings were in Agreement with Radiology reports. 

The healing effect of heparin on gastric ulcer and its underlying mechanisms were studied. The influences of protamine on these effects were also investigated. Gastric ulcer was induced by acetic acid in rats. Heparin (100-1000 U/kg i.v.) was given once daily for 4 or 7 days. Ulcer area was measured; gastric mucosal regeneration, proliferation, and angiogenesis were determined by histological o...

Gastric ulcer healing is a complex process that is regulated by several promoting factors including COX-2 and iNOS. Diabetes mellitus is usually associated with delayed gastric ulcer healing. Hence, the current study was designed to investigate the effect of sitagliptin (dipeptidyl peptidase-4 inhibitor) on gastric ulcer healing and expression of iNOS and COX-2 in rat stomach.The study was cond...

Endoscopic hemostasis is a useful treatment modality for gastric ulcer bleeding. However, it is sometimes difficult to achieve hemostasis in cases with arterial bleeding, especially those complicated with vascular abnormalities. We describe a case with gastric ulcer bleeding from a variant left gastric artery accompanied by congenital absence of the splenic artery. A 50-year-old female was admi...

BACKGROUND The presence of gastric metaplasia allows helicobacter pylori to colonise the duodenum and this condition is thought to be acquired as a response to acid hypersecretion. This functional disorder, however, is present only in a subgroup of duodenal ulcer patients and, in addition, surface gastric metaplasia has been frequently found in the proximal duodenum of normal subjects and patie...

Abstract Background Combretum paniculatum (Combretaceae) Vent. is commonly used in traditional medicine to treat ulcers and gastrointestinal disorders, including distended spleens the liver. This study investigated gastroprotective effects of C. leaf extract its fractions on absolute ethanol-induced gastric rats explored their endogenous antioxidant (SOD, MDA, GSH, Catalase) levels. Butanol, n-...