Aim To determine predictors and outcomes of extubation failure in extremely preterm (EP) infants born <28 weeks' gestational age (GA). Methods Retrospective clinical audit across two tertiary-level neonatal intensive care units Melbourne, Australia. Two-hundred four EP who survived to their first from mechanical ventilation. Extubation (re-intubation) within 7 days after the extubation. Results...

BACKGROUND Identifying patients at high risk of post-extubation acute respiratory failure requiring respiratory or mechanical cough assistance remains challenging. Here, our primary aim was to evaluate the accuracy of easily collected parameters obtained before or just after extubation in predicting the risk of post-extubation acute respiratory failure requiring, at best, noninvasive mechanical...

N Engl J Med 2014;370:e4. DOI: 10.1056/NEJMvcm1300964 Copyright © 2014 Massachusetts Medical Society. Overview Endotracheal extubation refers to the removal of an endotracheal tube from the trachea. This procedure is commonly performed in operating rooms, postanesthesia care units, and intensive care units. This review focuses on extubation of the trachea after general anesthesia and short-term...

OBJECTIVE To review a large population of children receiving mechanical ventilation to establish a baseline rate of extubation success and failure and to identify those characteristics that place a patient at greater risk of failing planned extubation. DESIGN Retrospective chart review. SETTING University-affiliated children's hospital with a 20-bed pediatric ICU. PATIENTS All 632 patient...

Objective: Positive pressure ventilation is known to have a deleterious effect on pulmonary blood ̄ow in patients with Fontan physiology. We evaluated the hemodynamic effects of pain free, spontaneous, non-positive pressure ventilation in patients undergoing Fontan staging procedures or completion. Fontan procedures, with creation of low pressure passive pulmonary circulation. Methods: Between ...

Introduction: Objective: To evaluate the utility of high-frequency physiologic data during extubation process and other clinical variables for describing profile failure in neonatal patients with hypoplastic left heart syndrome post-Norwood procedure. Methods: Design: Single-center, retrospective analysis Extubation events were collected from January 2016 until July 2021. was defined as need re...

INTRODUCTION To determine whether subjecting patients to 100 ml of additional dead space after a 120-minute weaning trial could predict readiness for extubation. METHODS This was a prospective, non-randomised pilot study in an intensive care unit at a university hospital with 14 beds. It included all non-tracheostomised patients with improvement of the underlying cause of acute respiratory fa...

BACKGROUND The authors prospectively evaluated the occurrence and outcomes of unplanned extubations (self-extubation and accidental extubation) and reintubation after weaning, and examined the hypothesis that these events may differ regarding their influence on the risk of nosocomial pneumonia. METHODS Data were taken from a prospective, 2-yr database including 750 mechanically ventilated pat...