The Antivirogram and PhenoSense assays are widely used phenotypic tests for HIV drug resistance. There are limited data on the reproducibility of each assay, and little is known about the correlation between the two. Using data from the Stanford HIV drug resistance database, we performed a comprehensive analysis of the reproducibility of each assay, and calculated the correlation and concordanc...

The detection of new designer drugs is often a difficult issue in forensic urine drug testing as immunoassays are the primary screening methodology for drugs of abuse in many of these laboratories. Cross-reactivity of compounds with immunoassay kits can either aid or complicate the detection of a variety of drug and drug metabolites. For instance, emerging designer drugs that share structural s...

The prevalence of drug-resistant strains of Mycobacterium tuberculosis (M. tb) emphasizes the need for new antitubercular drugs. An essential component of the drug discovery process is the development of tools to rapidly screen potential drug libraries against important biological targets. Similarly to well-documented M. tb targets, the antigen 85 (Ag85) enzymes are involved in the maintenance ...

Abstract The aim of the current study was to evaluate therapeutic potentials Hydroxyquinoline Sulfanilamide (HSM) for Alzheimer’s disease in a mice model Streptozotocin (STZ)-induced diabetes. antioxidant analysis brain homogenates carried out by catalase (CAT) assay, reduced glutathione (GSH) and lipid peroxidation (LPO) assay. Biochemical blood plasma conducted peroxidase (POD) assay superoxi...