Cushing's syndrome is a condition characterized by elevated cortisol levels that can result from either augmented endogenous production or exogenous administration of corticosteroids. The predisposition to fungal infections among patients with hypercortisolemia has been noted since Cushing's original description of the disease. We describe here a patient with endogenous Cushing's syndrome secon...

The aim of this study was to investigate the immunomodulatory effects of Spirulina platensis (S.platensis) by measuring the levels of serum interleukin (IL)-4, IL-10, IL-17, tumor necrosis factor(TNF)-α and interferon (IFN)-|γ| in mice suffered from systemic candidiasis and breast cancer. Theaqueous extract of S. platensis was selected for this study. Balb/C female mice were inoculated withCand...

Reintroducing URA3 to its native locus in Candida albicans not5, not3, bur2, and kel1 disruption mutants enabled us to directly compare strains with control strain CAI-12. We showed that URA3 position affected orotidine 5'-monophosphate decarboxylase activity, hyphal morphogenesis, adherence, and mortality in murine disseminated candidiasis. After URA3 was reintroduced to its native locus, only...

Candida is a common cause of oral mucous membrane and skin infections in newborn infants. Disseminated candidiasis and Candidemia have become a frequent problem in neonatal intensive care unit [1]. Candida species are frequently encountered as part of the human commensal flora. Colonization by Candida spp. is the most impor tant risk factor for development of Candidemia and IFI in pre mature in...