In a consecutive series of 100 female patients undergoing abdominal surgery muscular relaxation was obtained in half with dimethyltubocurarine and in half with toxiferine. The required dose of these relaxants (mg/m body surface) showed a lower individual variation than the requirements of any other non-depolarizing relaxants investigated under similar conditions. Neostigmine 0.5 mg reversed the...

ORIGINAL ARTICLES Leprosy and Childhood /. A. Kinnear Brown 173 The Mtoko Quintuplets F. Morley Smith and A. W. Husband 181 Muscle Relaxants in Anaesthesia 5. B a d e r ............................185 The Retroverted Uterus K. Duff ................................. 181 Effects of Certain Diseases on Population M. G e lfa n d ....................... 181 African Leishmaniasis B. K irk ..............

The aim of this study was to investigate the influence of chronic dexamethasone (Dex) administration on rat diaphragm sensitivity to non-depolarizing muscle relaxants (NDMRs) and muscular nicotinic acetylcholine receptor (nAChR) expression, which may help direct future administration of NDMRs. Adult male Sprague-Dawley rats were randomized to receive a daily intraperitoneal injection of Dex (60...