Dermal fibroblasts are a dynamic and diverse population of cells whose functions in skin in many respects remain unknown. Normal adult human skin contains at least three distinct subpopulations of fibroblasts, which occupy unique niches in the dermis. Fibroblasts from each of these niches exhibit distinctive differences when cultured separately. Specific differences in fibroblast physiology are...

T he rapid growth of the World Wide Web and advances in networking technology have made it more important than ever to secure personal computers and operating systems. Individual users as well as enterprises need to know that the systems they are using will not divulge personal or copyrighted information to hackers or accept viruses, worms, Trojan horses, or unsolicited e-mail that can slow or ...

Real-time continuous glucose monitoring (RT-CGM) is the latest technological breakthrough in diabetes care. Despite its limitations of lag time between sensor and blood glucose, the need for calibration, false detection of and failure to detect hypoglycemia, and mild discomfort or skin irritation reported in some users, RT-CGM is a highly beneficial tool that can be used to detect nocturnal or ...

The CEAs are sprayed, fan-like from a nozzled syringe onto severely burnt areas, prepared (ideally) with a patchwork of grafted skin. About half of the cells fall face down and grow because of the enzymes they secrete (being non-confluent), thus adhering to the recipient bed to proliferate. The beauty of Wood’s ‘spray-on skin’ (besides the speed of intervention so crucial for burns treatment), ...

Psoriasis is a common inflammatory condition involving the skin, scalp, nails and joints. It significantly increases the risk of cardiovascular events and death in those affected, above Framingham Risk Score (FRS) prediction alone 1 . There is a dose-response element; those with the most severe psoriasis (assessed by the psoriasis area severity index (PASI) score) are at the greatest risk. A UK...