Given a graph G = (V, E) and a weight function on the edges w : E 7→ R, we consider the polyhedron P (G, w) of negative-weight flows on G, and get a complete characterization of the vertices and extreme directions of P (G, w). As a corollary, we show that, unless P = NP , there no output polynomial-time algorithm to generate all the vertices of a 0/1-polyhedron. This strengthens the NP-hardness...

The standard treatment for advanced ovarian cancer consists in complete cytoreductive surgery (CRS) and intravenous combination chemotherapy with a platinum compound and a taxane. Although response rates to initial therapy are high, many patients will recur and die of peritoneal carcinomatosis. The addition of Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) to the standard therapy aims at inc...

Natural disasters can severely impact transportation networks. In the hours and days following a major flooding event, knowing the location and extent of the damage is crucial for incident managers for a number of reasons: it allows for emergency vehicle access to affected areas; it facilitates the efficient rerouting of traffic; it raises the quality and reduces the cost of repairs; and it all...

In the recent years, heterogeneous network (HetNet) is used to improve the spectral efficiency and network capacity of Long Term Evolution-Advanced (LTE-A). Although, it has huge traffic congestion due to numerous numbers of mobile users and data terminals, leads to problems of cooperation between Macro-cell and Pico-cells. One of the major interference sources in LTE-A is Common Reference Sign...

The effect of head positioning is often not accounted for when optimising performance in the back squat exercise. primary aim study was to identify most advantageous position peak power (PP), velocity (PV) and force (PF) A secondary favourable position. Twenty male rugby union players performed 1x3 repetitions at 75% one repetition maximum (1RM) determine their preferred pre-intervention positi...

Wyrok SN wskazuje na pojawianie się w polskiej praktyce kontraktowej nowych klauzul umownych we wzorcach umownych, które wydają gwaranci (banki i ubezpieczyciele ,art. 384 k.c.). Chodzi o klauzule, mogą służyć ochronie dłużnika (np. wykonawcy robot budowlanych, art. 647 k.c.) razie skorzystania przez wierzyciela (inwestora) z gwarancji „ pierwsze żądanie” bezpodstawnie tj. bez spełnienia warunk...

BACKGROUND The prevalence of patients with chronic rhinosinusitis (CRS) refractory to traditional therapy appears to be on the increase. In these cases, CRS tends to be associated with bronchial asthma (BA), especially, aspirin-intolerant asthma (AIA). On the other hand, arachidonic acid metabolites have been extensively investigated in the pathogenesis of BA. We sought to assess the role of pr...

W e define a natural variant of NP, MAX NP, and also a subclass called MAX SNP. These are classes of optimization problems, and in fact contain several natural, well-studied ones. W e show that problems in these classes can be approximated with some bounded error. Furthermore, we show that a number of common optimization problems are complete for MAXSNP under a kind of careful transformation (c...

Objective—To determine the extent to which child restraint system (CRS) misuse can be evaluated by parental survey. Methods—A cross sectional survey was conducted at eight CRS clinics from May to October, 1998. Before CRS inspection, parents were administered a structured interview to identify distinct characteristics of restraint use and misuse. After the interview, a certified child passenger...

BACKGROUND A subset of patients with chronic rhinosinusitis (CRS) has refractory disease. The risk factors for refractory CRS include atopy, a disrupted mucociliary transport system, medical conditions affecting the sinonasal tract mucosa, and immunodeficiency. METHODS We review four primary immunodeficiencies reported in individuals with CRS: common variable immune deficiency (CVID), selecti...