نتایج جستجو برای: cortical spreading depression

تعداد نتایج: 270778  

Journal: :Medical research archives 2023

Objectives: The discovery of cortical spreading depression 80 years ago by Leão was intimately connected to epilepsy research. In our studies we found that monitoring brain hemodynamics, metabolic ionic and electrical activities are very similar in the two pathophysiological events. Here presenting coupling between while mitochondrial nicotinamide adenine dinucleotide-NADH together with other p...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009
Yilong Cui Tadayuki Takashima Misato Takashima-Hirano Yasuhiro Wada Miho Shukuri Yasuhisa Tamura Hisashi Doi Hirotaka Onoe Yosky Kataoka Yasuyoshi Watanabe

UNLABELLED Neurogenic inflammation triggered by extravasation of plasma protein has been hypothesized as a key factor in the generation of the pain sensation associated with migraine. The principal immune cell that responds to this inflammation is the parenchymal microglia of the central nervous system. METHODS Using a PET technique with (11)C-(R)-[1-(2-chlorophenyl)-N-methyl-N-(1-methyl-prop...

2007
Nathan J. Downey Joann M. Stock Robert W. Clayton Steven C. Cande

[1] The Osbourn Trough is a fossil spreading center that rifted apart the Manihiki and Hikurangi Plateaus during Cretaceous time. Previous models of the Osbourn spreading center are based on data collected near the trough axis, and therefore only constrain the history of the Osbourn spreading center during the last few Ma of spreading. Our data set includes multibeam data collected northward to...

2009
Markus A. Dahlem Rudolf Graf Anthony J. Strong Jens P. Dreier Yuliya A. Dahlem Michaela Sieber Wolfgang Hanke Klaus Podoll Eckehard Schoell

We present spatio-temporal characteristics of spreading depolarizations (SD) in two experimental systems: retracting SD wave segments observed with intrinsic optical signals in chicken retina, and spontaneously occurring re-entrant SD waves that repeatedly spread across gyrencephalic feline cortex observed by laser speckle flowmetry. A mathematical framework of reaction-diffusion systems with a...

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