Curcumin (CCM) is an important molecule for achieving cancer theranostics because CCM is a naturally-occurring biocompatible material that exhibits both anticancer activity and strong fluorescence property that can be used for bio-imaging. However, CCM has never been utilized in clinical trials due to its extremely low water solubility, its rapid hydrolysis in aqueous conditions at neutral pH, ...

Following the success of CORBA based systems the OMG has standardized the CORBA Component Model (CCM) to improve the implementation process of large distributed systems. The European project COACH [16] has been set up to build an Open Source development platform to construct CCM applications. As part of COACH a toolset for CCM components and system testing has been defined and implemented. This...

omotopy analysis method (ham) is a promising method for handling func-tional equations. recent publications proved the eectiveness of ham in solvingwide variety of problems in dierent elds. ham has a unique property whichmakes it superior to other analytic methods, this property is its ability to con-trol the convergence region of the solution series. in this work, we claried theadvantages ...

this paper deals with scrutinizing the convergence properties of iterative methods to solve linear system of equations. recently, several types of the preconditioners have been applied for ameliorating the rate of convergence of the accelerated overrelaxation (aor) method. in this paper, we study the applicability of a general class of the preconditioned iterative methods under certain conditio...

in this paper, we studied the numerical solution of nonlinear weakly singular volterra-fredholm integral equations by using the product integration method. also, we shall study the convergence behavior of a fully discrete version of a product integration method for numerical solution of the nonlinear volterra-fredholm integral equations. the reliability and efficiency of the proposed scheme are...

In this paper we propose a novel method of adding turbulence to low-res. smoke simulation. We consider the physical properties of such low-res. simulation and add turbulence only to the appropriate position where the value of the energy cascade ratio is judged as physically correct. Our method can prevent noise in the whole region of fluid surfaces which appeared with previous methods. We also ...

This study aimed to elucidate the mode of action of curcumin (CCM) as an anticancer agent, and to investigate its effects on the proliferation and induction of apoptosis in HT29 human colon cancer cells. We examined the effect of CCM on two cysteine protease families, namely caspases and calpains, which are known to induce apoptosis in a number of cancer cells. We demonstrated that CCM reduces ...

Whilst chemical cleavage of mismatch (CCM) detects all point mutations in DNA, its widespread use has been hampered by the complex multistage methodology and the need for toxic chemicals, in particular osmium tetroxide. Here we show that osmium tetroxide can be replaced by potassium permanganate, giving the same spectrum of mutation detection, but with greater sensitivity. The use of potassium ...