The amplification and typing conditions for the 13 core CODIS loci and their forensic applicability were evaluated. These loci are CSF1PO, FGA, TH01, TPOX, vWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11. Results were obtained using the multiplex STR systems AmpFlSTR Profiler Plus and AmpFlSTR COfiler (Applied Biosystems, Foster City, CA), GenePrint PowerPlex (Promeg...

High throughput sequencing (HTS) of DNA forensic samples is expanding from the sizing of short tandem repeats (STRs) to massively parallel sequencing (MPS). HTS panels are expanding from the FBI 20 core Combined DNA Index System (CODIS) loci to include SNPs. The calculation of random man not excluded, P(RMNE), is used in DNA mixture analysis to estimate the probability that a person is presen...

I. Moltes de les causes de la corrupció es troben en la falta de desenvolupament del sistema democràtic, per no haver creat mecanismes reals de participació ciutadana en el control eficaç de les seues institucions, així com en l’absència de rendició de comptes dels responsables polítics davant de la ciutadania i dels seus òrgans de representació. II. La corrupció deteriora l’Estat de dret i imp...

Advances in sequencing technology have enabled DNA profiling to become a staple in criminal forensics. Short tandem repeats (STRs) embedded in an individuals’ genetic code enable authorities to take advantage of biological variability to accurately identify and discriminate among people. According to the National DNA Index System (NDIS), CODIS, a DNA database containing more than 12 million pro...

In 2013, the Official Journal of Federation Mexico listed key challenges facing Mexico's judicial institutions: a lack public trust due to widespread corruption and systematic failure prosecute convict criminals (DOF, 2014). A plan address these issues ensued. Written by National Conference on Administration Enforcement Justice, this consisted institutional reforms be carried out Mexican judici...

The goal of this project is to develop novel STR multiplexes with reduced amplicon sizes for the analysis and detection of degraded and contaminated DNA. In such samples, DNA template can become highly fragmented due to bacterial, biochemical, or oxidative processes, and the possibility of finding an intact target sequence for PCR is greatly reduced. In this project researchers are developing a...

The proven utility of forensic DNA evidence has increased the demand for DNA analysis services. Although conventional DNA analysis techniques are effective, they are time-consuming and laborious, which contributes to the overall cost and to an overwhelming backlog of forensic casework samples with possible biological evidence. Research efforts have focused on the development of more rapid and e...