SUMMARY Two patients with a chronic progressive myelopathy were successfully surgically treated and idiopathic hypertrophic spinal pachymeningitis (IHSP) was found on histology. In both patients, an extensive extramedullary mass of low T2 signal with peripheral contrast enhancement was compressing the spinal cord on MR imaging. This imaging appearance in patients with chronic progressive myelop...

COPD is a slowly progressive disorder defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) as “A common preventable and treatable disease characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airway and the lungs to noxious particles or gases. Exacerbation and comorbidities contribu...

idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. polymyositis (pm), dermatomyositis (dm) and inclusion body myositis (ibm) are the three major subsets based on distinct clinical and histopathological features. since the pathogenesis remains unclear, therapeutic approaches actually compr...

Chronic kidney disease is a slow and progressive loss of function over period several years. Eventually, person will develop permanent failure. The aim the present study was to assess knowledge family care givers regarding hemodialysis chronic renal failure patients in selected hospitals Jabalpur. research design for this descriptive nature. target population method sampling purposive sampling....

Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D.   Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls.   Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN-   ¹ gene was evaluated at position 5’UTR...

background vitamin d deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. it is also shown that vitamin d deficiency may result in chronic liver disease or liver cirrhosis. in this study, we aimed to systematically review the literature wherein the relationship between vitamin d deficiency and the severity of chronic liver disease or liver cirrhosis had...

PURPOSE We determined the clinical utility of proton MR spectroscopy in defining the extent of disability in benign versus secondary-progressive multiple sclerosis (MS). METHODS Thirty patients with clinically definite MS, including 16 patients with benign MS and 14 with secondary-progressive MS, and a group of 13 healthy volunteers were studied with combined stimulated-echo acquisition mode ...

We present a case of a 10-year-old boy who presented with bilateral diffuse subconjunctival hemorrhages after spinning rapidly on a carousel attached to an electrical scooter. We present his clinical course and discuss the physics and pathophysiology of this unique mechanism of ocular trauma.

Multiple sclerosis is a severe disorder of the central nervous system. This chronic and progressive disease involves unpredictable episodes of inflammatory attacks. It can cause functional limitations, disability and reduced quality of life. Pain is a common and significant problem in lots of people with multiple sclerosis (MS). And it is inversely correlated with aspects of life quality in ind...

How providers of external quality assessment (EQA) programmes relate to and interact with the monitors and watchdog of clinical laboratory performance in the UK is described. With regard to the quality of antibiotic assays, the changes in methodologies and in performance quality between 1971 (when the UK NEQAS for Antibiotic Assays began) and 1999 is reviewed. How improvements in performance an...