Tumour cellularity, the relative proportion of tumour and normal cells in a sample, affects the sensitivity of mutation detection, copy number analysis, cancer gene expression and methylation profiling. Tumour cellularity is traditionally estimated by pathological review of sectioned specimens; however this method is both subjective and prone to error due to heterogeneity within lesions and cel...

Radiation kills or reduces reproductive capacity of proliferating cells, including stem cells. In the oral mucosae this can result in a decline in the number of cells in the tissue which, if severe enough, will result in the formation of an ulcer when the cellularity essentially reaches zero. We have used histometric measurements of cellularity following exposure to radiation in mouse ventral t...

To investigate the ulcer protective and antisecretory properties of the methanolic extract of Butea monosperma (BM) bark with relation to antioxidant studies. The study was done on male albino rats.   Gastric ulcers were induced by Aspirin, Alcohol and Pylorous ligation. Lansoprazole was used as the standard drug for comparison. The free radical scavenging potential of the bark of BM ...

We report the enhanced augmentation of cardiac output in a 60-year-old man who underwent percutaneous coronary intervention with drug-eluting stent implantation for a large anteroseptal ST-segment-elevation myocardial infarction. Because of persistent systemic hypotension during the procedure, a 50cc, 8-Fr Mega intra-aortic balloon was inserted, used for 24 hours, and removed without complicati...

Bone marrow biopsies (244) performed with a Jamshidi needle were evaluated in 53 children with leukemia or aplastic anemia. Adequate specimens were obtained in 85%. Results of cellularity estimated by biopsy were compared to the cellularity of the aspirate versus volumetric determination of the myeloid-erythroid layer (buffy coat). A wide discrepancy was noted between marrow cellularity confirm...

introduction: bone marrow (bm) is a known source of mesenchymal stem cells (mscs) that are used for cell therapy. this study attempts to identify if the wharton’s jelly (wj) is a suitable substitute for bm as a source for mscs. materials and methods: a population of human wj and bm stem cells were isolated and incubated with fluorescein conjugated antibodies for five specific msc markers. cell ...